hybridization


Also found in: Dictionary, Thesaurus, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to hybridization: DNA hybridization

hybridization

 [hi″brid-ĭ-za´shun]
1. the production of hybrids.
fluorescent in situ hybridization (FISH) a genetic mapping technique using fluorescent tags for analysis of chromosomal aberrations and genetic abnormalities. Called also chromosome painting.
molecular hybridization in molecular biology, formation of a partially or wholly complementary nucleic acid duplex by association of single strands, usually between DNA and RNA strands or previously unassociated DNA strands, but also between RNA strands; used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands.

hy·brid·i·za·tion

(hī'brid-i-zā'shŭn),
1. The process of breeding a hybrid.
2. Crossing over between related but nonallelic genes.
3. The specific reassociation of complementary strands of polynucleic acids, for example, the formation of a DNA-RNA hybrid.
4. The process or act of forming a macromolecular hybrid in which the subunits are obtained from different sources.
Synonym(s): crossbreeding

hybridization

Molecular biology The formation of a complex of complementary nucleotides; hybridization allows determination of the relatedness or sequence 'homology' between 2 strands of nucleic acids, and precise ID of short–up to 20 kb segments of DNA–Southern blot or RNA–Northern blot

hy·brid·i·za·tion

(hī'brid-ī-zā'shŭn)
1. The process of breeding a hybrid.
2. Crossing over between related but nonallelic genes.
3. The specific association of complementary strands of polynucleic acids, e.g., the formation of a DNA-RNA hybrid.
Synonym(s): hybridisation.

hybridization

See MOLECULAR HYBRIDIZATION.

hy·brid·i·za·tion

(hī'brid-ī-zā'shŭn)
1. The process of breeding a hybrid.
2. Crossing over between related but nonallelic genes.
Synonym(s): hybridisation.
References in periodicals archive ?
- Chromogenic In Situ Hybridization (CISH) (Technique) Market Share Breakdown of Key Players: 2019 & 2025
It shows that he was trapped in such a situation due to hybridization and cultural transformation.
To determine Rf locus location on chromosome, Allium galanthum genomic DNA was used as probe DNA, while for blocking DNA, Allium fistulosum genomic DNA was utilized for in situ hybridization of [F.sub.1] hybrids of both species and backcross generations.
Hybridization clues such as those seen in the Oase fossil may dot the skulls of living animals as well.
We can now better understand the opinions of Maharal and Ibn Ezra, which related the general prohibition against hybridization to the concept of sexual morality.
Chivukula on several projects, including the HER2 dual in situ hybridization (DISH) project.
In conclusion, we have demonstrated the DNA immobilization and hybridization on GNPs-modified Si[O.sub.2] thin film as electrode device.
The authors conclude that the process of hybridization (defined as the production of offspring through the interbreeding between individuals of genetically distinct populations), the factors governing the expression of morphology in hybrid individuals, and the extent of reproductive isolation between species should be given further consideration in future research projects.
considered that the viable uniparental progenies from interspecific hybridization might result from contamination by brood from pure crosses because nonparental bands were found in protein electrophoresis of F1 progeny.
The hybridization probes for chromosomes 13, 18, and 21 were modified from the original probe-mix of the P095 kit (see Fig.
Array-based comparative genomic hybridization (aCGH) makes it possible to assess the chromosome count and perform a high-resolution search for microduplications and deletions.