huperzine A


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huperzine A

Chinese medicine
An ACE (acetylcholinesterase)-inhibiting sesquiterpene alkaloid found in the plant firmoss (Huperzia serrata). While not FDA-approved for such, it is sold in the US as a memory-enhancing dietary supplement; it is used in traditional Chinese medicine for oedema, fever and blood dyscrasia. Like tacrine, HA increases synaptic acetylcholine by inhibiting acetylcholinesterase; early data suggests that it may have some benefit in patients with Alzheimer's disease, epilepsy and in myasthenia gravis.

Adverse effects
Mild cholinergic effects, as well as dyspnoea, chest pain, rash, pruritus, gastritis, diarrhoea, vomiting, hyperactivity and insomnia.
References in periodicals archive ?
Some of the components include 1) Acetyl-L-Carnitine, Alpha GPC, Huperzine A and L-Tyrosine for enhanced mental performance; 2) Beet Root Extract, L-Arginine for improved blood circulation; 3) Beta Alanine, Caffeine, L-Citrulline for energy, endurance and strength; and 4) Coconut Water for hydration support.
BODY FUEL: ALPINE PRODUCTS
BIS-001 is a highly potent form of huperzine A, a synthetic extract of a traditional Chinese medicine with a long history of safe use.
Biscayne Forms Neurotherapeutics Business, Closes USD 3m Venture Financing
Q My sister takes a supplement called huperzine A because she heard it helps preserve memory as you age.
Ask the experts
A Huperzine A is a dietary supplement made from a type of club moss.
Q & A
Q Is huperzine A helpful for people with memory problems?
Ask the doctor
Huperzine A (Hup A), a new alkaloid and highly reversible ChE-I, is isolated from Huperzia serrata.
Huperzine A in the treatment of Alzheimer's disease and vascular dementia: a meta-analysis
One unique supplement component of Brain Power Basics is NeuroVite Plus, a phytonutrient-based multivitamin and antioxidant blend with a complete range of digestive enzymes, more than 50 nutrients and minerals, and a proprietary" brain--boosting blend." Additionally, the line includes Omega 3 Power, which provides 1,600 mg of omega 3 fatty acids from ultra-purified fish oil; and Brain & Memory Power Boost, which includes N-Acetyl-Cysteine (NAC), phosphatidylserine, huperzine A and acetyl-l-carnitine, vinpocetine and gingko biloba.
Brain Power Basics
Huperzine A (HupA) is a reversible and selective inhibitor of acetylcholinesterase (AChE), and it has multiple targets when used for Alzheimer's disease (AD) therapy.
Huperzine a activates Wnt/B-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model
Huperzine A, a Lycopodium alkaloid produced by Chinese folk herb Huperzia serrata (Lycopodiaceae), has been shown to be a promising agent for the treatment of Alzheimer's disease due to its potent acetylcholinesterase (AChE) activity, as well its efficacy in the treatment of memory of aged patients.
Huperzia quadnfariata and Huperzia reflexa alkaloids inhibit acetylcholinesterase activity in vivo in mice brain
The memory-enhancing substance I'm talking about is an alkaloid called Huperzine A. It comes from the Chinese club moss, Huperzia serrata.
This little-known nutrient improves memory, even in people with Alzheimer's disease
Washington, August 26 (ANI): Scientists at Yale University have developed the first practical method to create a compound called huperzine A, which occurs naturally in a species of moss found in China, believed to treat Alzheimer's disease.
Alzheimer's-fighting Chinese herb compound synthesized
The results were reported in ConsumerLab.com's "Product Review: Supplements for Memory & Cognition Enhancement," which focuses on three ingredients that have shown some promise in improving memory: Ginkgo biloba, huperzine A, and acetyl-L-carnitine.
Adulteration suspected with some 'memory' supplements
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