The company also announced that it has exclusively licensed key patents from Harvard University for the use of Insero's lead compound huperzine
as a treatment for epilepsy and other indications.
To the best of our knowledge, other than huperzine
A (Zhang and Tang, 2006), this is the only report of an AChE inhibitor displaying associated neuroprotective properties.
NASDAQ: NHPI), a New York-based biopharmaceutical company focused on developing innovative drugs for the treatment of neurodegenerative diseases, today announced that it had entered into an agreement with Numoda Corporation ("Numoda") pursuant to which Numoda will review the results of Neuro-Hitechs' recently completed Phase II clinical trial of Huperzine
A in mild to moderate Alzheimer's disease patients.
A is a biochemical component of the Chinese club moss Huperzia serrata.
BIS-001 is a fully synthetic version of the extracted Chinese medicine huperzine
A is another natural choline esterase inhibitor isolated from the Chinese herb Huperzia serrata shown to improve cognitive function and general daily activity (Yang et al.
From 2006 to 2014, the companies made $96 million selling the supplement, which contains vinpocetine, huperzine
A, and acetyl-L-carnitine.
126-128) Herbal cholinergic support may include phosphatidyl choline, pantothenic acid, huperzine
A (from Huperzia serrata), and N-aceytl-L-carnitine.
Hilmas worked as a physiologist and principal investigator for the US Army Medical Research Institute of Chemical Defense, investigating the efficacy of two dietary ingredients, galantamine and huperzine
have medicinal properties, and have yielded huperzine
A used to treat neurodegenerative disorders such as Alzheimer's Disease (for review, see Cheng et al.
A (HupA), a cholinesterase inhibitor naturally derived from the Chinese herb Lycopodium serratum (or Huperzia serrata), has better penetration through the blood-brain barrier, higher oral bioavailability and longer duration of AChE inhibitory action than tacrine, donepezil, and rivastigmine.
The memory-enhancing substance I'm talking about is an alkaloid called Huperzine