hungry bones syndrome
Lab Increased calcitriol, markedly decreased Ca2+ (e.g., 1.5 mmol/L—US: 6 mg/dl or lower), decreased phosphorus, decreased magnesium, reactive increase in PTH—if there is residual secretion; the danger lies in attributing symptoms to acidosis, which may accompany and exacerbate the complex Management Vitamin 1,25(OH)D2
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
hungry bones syndromePost-parathyroid surgery recalcification tetany Metabolism Transient hypoparathyroidism due to resection of significant portions of a hyperactive parathyroid gland; HBs follow high pre-operative PTH–due to excess PTH secretion as occurs in parathyroid hyperplasia and adenoma, high alk phos and extensive bone demineralization, resulting in a rapid 'rebound' recalcification of bones after prolonged hypocalcemia; bone hunger is exacerbated by a pre-existing compromise in renal function Radiology Mottled bone hypodensity Lab ↑ Calcitriol, ↓↓↓ Ca2+–eg, 1.5 mmol/L–US: 6 mg/dl or lower, ↓ phosphorus, ↓ magnesium, reactive ↑ in PTH–if there is residual secretion; the danger lies in attributing Sx to acidosis, which may accompany and exacerbate the complex Treatment Vitamin 1,25(OH)D2
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
hungry bones syndromeA condition that sometimes follows removal of a tumour that has been causing excessive output of parathyroid hormone (HYPERPARATHYROIDISM). Calcium is withdrawn so rapidly from the blood that lowered blood levels occur, causing TETANY.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005