hungry bone syndrome

hungry bone syndrome

Hypocalcemia that develops in hyperparathyroid patients treated with parathyroidectomy or in patients with end-stage renal disease treated with calcimimetic drugs. It is caused by a sudden decrease in serum parathyroid hormone levels, which in turn increase the uptake of calcium, magnesium, and phosphate by bone. Clinical consequences include tetany (repetitive muscle twitching) esp. in patients whose calcium deficiency is severe.
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The patient did not present with hungry bone syndrome in the immediate postoperative period, and postoperative PTH levels were normal [52.2 (normal range, 15-68) pg/mL]; calcium level was 91.8 (normal range, 88-106) mg/L.
Hypocalcemia is a common complication after parathyroidectomy and in severe cases is also referred to as hungry bone syndrome [14]; it seems to originate from a rapid drop in the PTH levels and may be more common in patients with secondary hyperparathyroidism.
Hungry bone syndrome may have been an important component leading to the very low serum calcium levels [14].
This is the first report, to our knowledge, of discontinuation of anticoagulants causing autoinfarction of a large parathyroid tumor and resulting hungry bone syndrome.
The initiation of anti-thyroid drugs may lead to excessive bone remineralization resulting in hungry bone syndrome (HBS), characterized by hypocalcemia, hypophosphatemia, and hypomagnesemia (3).
Hungry bone syndrome (HBS) refers to a severe, rapid and prolonged hypocalcemia associated with hypophosphatemia and hypomagnesaemia that are the consequences of suppressed parathyroid hormone levels at patients with prior high bone turnover [1-6, 9, 11, 12].
Post-surgical hypocalcaemia was treated with calcium supplementation, which was probably caused by hungry bone syndrome and bipfoshonate treatment.
Postoperative persistence of elevated PTH levels should be interpreted with serum calcium, phosphorus, and vitamin D levels for the differential diagnosis of unsuccessful surgery, hungry bone syndrome, and vitamin D deficiency.
One noted side effect of treatment with osteoprotegerin was hypophosphatemia and hypocalcemia with secondary hyperparathyroidism, "which occurred as bone resorption was abruptly inhibited (the so-called hungry bone syndrome)," Dr.
Acidosis (correction of), blood transfusions (massive), epinephrine, hungry bone syndrome, insulin/glucose/refeeding syndrome, pancreatitis (acute)
For Hungry bone syndromes use calcium supplements and Vitamin D.
He also mentioned about likely complications, hungry bone syndromes. Symptomatic Patients with failure of medical therapy should go for surgery but those patients who are not suitable for surgery should be offered medical therapy.