humoral immunity

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hu·mor·al im·mu·ni·ty

immunity associated with circulating antibodies, in contradistinction to cellular immunity. The inherent range of activity of antibody specificities is wide but proliferation of antigen-specific B cells occurs rapidly during infections leading to rapid increases in antibody titers with enhanced affinity for the inciting agent, and a more effective and directed response.

humoral immunity

n.
Immunity involving the transformation of B-lymphocytes into plasma cells that produce and secrete antibodies to a specific antigen.

hu·mor·al im·mu·ni·ty

(hyū'mŏr-ăl i-myū'ni-tē)
Immunity associated with circulating antibodies, in contradistinction to cellular immunity.
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HUMORAL IMMUNITY

humoral immunity

The protective activities of antibodies against infection or reinfection by common organisms, e.g., streptococci and staphylococci. B lymphocytes with receptors to a specific antigen react when they encounter that antigen by producing plasma cells (which produce antigen-specific antibodies) and memory cells (which enable the body to produce these antibodies quickly in the event that the same antigen appears later). B-cell differentiation also is stimulated by interleukin-2 (IL-2) secreted by CD4+ T cells and foreign antigens processed by macrophages.

Antibodies produced by plasma B cells, found mainly in the blood, spleen, and lymph nodes, neutralize or destroy antigens in several ways. They kill organisms by activating the complement system; neutralize viruses and toxins released by bacteria; coat the antigen (opsonization) or form an antigen-antibody complex to stimulate phagocytosis; promote antigen clumping (agglutination); and prevent the antigen from adhering to host cells.

Synonym: B-cell–mediated immunity See: illustration; cell-mediated immunity; immunoglobulin
See also: immunity
References in periodicals archive ?
The humoral immune response in tuberculosis: its nature, biological role and diagnostic usefulness.
Effects of probiotic, prebiotic and synbiotic on performance and humoral immune response of female suckling calves.
This process appears as starting of the cellular and humoral immune response development.
B lymphocytes mediate the humoral immune response and are in charge of antibody production, expressing on their surface when they are mature: CD19, PAN B antigens (CD21, CD24) and surface immunoglobulins, in addition to major complex antigens of type II histocompatibility and complement receptors [1].
To assess the humoral immune response of the patient to Brucella antigens, the slide agglutination test with B.
The "early" seroconvertors, were significantly less anxious and less stressed than "late" seroconvertors, indicating that stress delayed the humoral immune response to hepatitis B vaccination.
In a recent study, we have shown that two commonly used imported vaccines induced good humoral immune response (Jamil et al., 2015).
The present study was planned to evaluate the effects of dietary ochratoxin A (OTA) in the presence and absence of a toxin deactivator on the organ weights, humoral immune response of broiler birds vaccinated against Newcastle disease (ND), hydropericardium syndrome (HPS) and infectious bursal disease (IBD).
HIV-1 Gag p24-Nef fusion peptide induces cellular and humoral immune response in a mouse model.
The humoral immune response in broilers was measured by injecting sheep red blood cells (SRBC), a nonpathogenic antigen.