human skin equivalent


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human skin equivalent

Graft made of living human skin grown in a laboratory and used, e.g., to treat leg ulcers in patients with peripheral vascular disease or diabetes mellitus. The graft bonds with healthy tissue in a wound from which necrotic tissue has been removed, improving healing. It is grown from foreskin removed from neonates but also contains bovine (cow) proteins, limiting its use to those with no allergy to these proteins.
Synonym: artificial skin; tissue-engineered skin
See also: equivalent
References in periodicals archive ?
The human skin equivalent supplied in our 24-well StrataTest([R]) plate offers not only an enhanced, high-quality in vitro testing model, it enables better prediction of in vivo biological response.
In addition to Apligraf(TM) manufactured human skin equivalent, the Company's product portfolio includes the GRAFTPATCH(TM) surgical product (recently cleared for marketing in the U.
The Company's lead product, Apligraf(tm) Human Skin Equivalent, was recently approved in Canada; its premarket approval application (PMA) is currently pending at the U.