human repeated patch insult

human repeated patch insult

The serial application of substances to the skin to test for reaction. The material is applied fresh to the same skin site every other day for 10 applications. Each application remains on for 48 hr. After a rest period of about 2 weeks, the test material is applied again for 48 hr to a different skin site than that originally used. This area is examined daily for the next 4 days for evidence of irritation. The test measures the ability of the test substance to cause sensitization or irritation reactions or both.
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