human monocytic ehrlichiosis
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human monocytic ehrlichiosisInfectious disease An infection by Ehrlichia chaffeensis Vector Lone Star tick–Amblyomma americanum, possibly also Dermacentor variabilis Reservoir Deer, possibly dogs or others Regions US, Europe, Africa Clinical Fever, malaise, headache, myalgia, rigors, sweating, anorexia, arthralgia, N&V, pharyngitis, rash, cough, diarrhea; with progression of HME, fever, headache, myalgia, anorexia, and arthralgia become more intense Lab CSF pleocytosis, E chaffeensis inclusions in monocytes, spleen and other tissues, BM hyperplasia–58%, hypoplasia–17% Diagnosis Romanovsky stains of circulating monocytes, EM, indirect immunofluorescence, PCR Complications Meningitis, interstitial pneumonia, GI and pulmonary hemorrhage, disseminated hemorrhage. Cf Human granulocytic ehrlichiosis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
hu·man mon·o·cyt·ic ehr·lich·i·o·sis(HME) (hyū'măn mon'ō-sit'ik er-lik'ē-ō'sis)
A febrile disease caused by Ehrlichia chaffeensis and transmitted by the Lone Star tick (Amblyomma americanum); similar to human granulocytic ehrlichiosis, except that inclusions are found in monocytes.
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