human monocytic ehrlichiosis


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human monocytic ehrlichiosis

human monocytic ehrlichiosis

Infectious disease An infection by Ehrlichia chaffeensis Vector Lone Star tick–Amblyomma americanum, possibly also Dermacentor variabilis Reservoir Deer, possibly dogs or others Regions US, Europe, Africa Clinical Fever, malaise, headache, myalgia, rigors, sweating, anorexia, arthralgia, N&V, pharyngitis, rash, cough, diarrhea; with progression of HME, fever, headache, myalgia, anorexia, and arthralgia become more intense Lab CSF pleocytosis, E chaffeensis inclusions in monocytes, spleen and other tissues, BM hyperplasia–58%, hypoplasia–17% Diagnosis Romanovsky stains of circulating monocytes, EM, indirect immunofluorescence, PCR Complications Meningitis, interstitial pneumonia, GI and pulmonary hemorrhage, disseminated hemorrhage. Cf Human granulocytic ehrlichiosis.

hu·man mon·o·cyt·ic ehr·lich·i·o·sis

(HME) (hyū'măn mon'ō-sit'ik er-lik'ē-ō'sis)
A febrile disease caused by Ehrlichia chaffeensis and transmitted by the Lone Star tick (Amblyomma americanum); similar to human granulocytic ehrlichiosis, except that inclusions are found in monocytes.
References in periodicals archive ?
A previous case of human monocytic ehrlichiosis in a 17-month-old girl in Venezuela has been demonstrated serologically (2).
Among these emerging pathogens are several species of Ehrlichia, small, gram-negative bacteria transmitted by arthropod vectors that can cause human disease, such as human monocytic ehrlichiosis (HME).
The two main pathogenic species are Ehrlichia chaffeensis, which causes human monocytic ehrlichiosis (HME), and the as-yet-unnamed agent of human granulocytic ehrlichiosis (HGE) (4).
The increasing deer population and expanding tick distribution may increase risk for human monocytic ehrlichiosis.
canis in humans (2) and human granulocytic ehrlichiosis as human monocytic ehrlichiosis in areas where the vector was not present (3).
The conclusions meet the criteria published by the American Society for Rickettsiology, in which a confirmed diagnosis of human monocytic ehrlichiosis (HME) is based on a "single serum titer of 256" in a patient with clinically compatible disease (5).
We present the first serologic evidence that the agents of human monocytic ehrlichiosis (HME) and HGE are present in Israel.
The emerging tick-borne zoonoses human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE) are underreported in the United States.
To the Editor: Human monocytic ehrlichiosis (HME), a tickborne zoonosis caused by the rickettsial pathogen Ehrlichia chaffeensis (Rickettsiales: Anaplasmataceae), is considered an emerging pathogen in the United States and, increasingly, in many countries around the world (1).

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