human leukocyte antigen


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human leukocyte antigen (HLA)

The human MAJOR HISTOCOMPATIBILITY COMPLEX.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

hu·man leu·ko·cyte an·ti·gen

(HLA) (hyū'măn lū'kō-sīt an'ti-jen)
Any of several members of a system consisting of the gene products of at least four linked loci (A, B, C, and D) and a number of subloci on the sixth human chromosome that have been shown to have a strong influence on human allotransplantation, transfusions in refractory patients, and some disease associations.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Fuchs et al., "Partially mismatched transplantation and human leukocyte antigen donor-specific antibodies," Biology of Blood and Marrow Transplantation, vol.
These findings support the theory that human leukocyte antigen class I-restricted cytotoxic T cells and human leukocyte antigen class II-restricted helper T cells play an important role in HBV chronicity.
4 A human leukocyte antigen test can establish probable individual identity through scientific analysis of hereditary protein material.
Using a genome editing approach the company engineers stem cells to prevent expression of polymorphic human leukocyte antigen (HLA) molecules, removing the cause of donor tissue rejection and creating Universal Donor Stem Cells that are compatible with every patient.
Goldhirsch, "Molecular pathways: human leukocyte antigen G (HLA-G)," Clinical Cancer Research, vol.
Therapeutic candidates will be developed in conjunction with CDI's world-leading position in human leukocyte antigen "haplobanking," which enables the therapeutic cells to be matched to the patient's immune system, potentially avoiding the need to co-administer immune suppressing drugs.
Human leukocyte antigen (HLA)-B51 has been recognized as the strongest genetic predisposing factor for BD.
Among these regions, they identified variants at the IL1RL1/IL18R1/IL18RAP and human leukocyte antigen (HLA) loci, both of which have been associated with bronchial asthma in recent GWAS.
Transplanting a kidney from a human leukocyte antigen (HLA)mismatched donor could eliminate the need for recipients to take immunosuppressive drugs to prevent rejection, according to the findings of a study published in a recent issue of Translational Medicine.
We describe 2 cases of bilateral Meniere disease with features resembling autoimmune inner ear disease in patients who were found to be carriers of human leukocyte antigen (HLA) B27.
Olerup SSP develops kits for genomic human leukocyte antigen (HLA) typing, a required step prior to a transplantation to match the donor and the recipient.

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