Serology disclosed IgG (1/160) and IgM (1/320) antibodies against human herpesvirus 7
(HHV-7) and IgG antibody against human herpesvirus 6 (HHV-6) (1/40).
(18) Human herpesvirus 7
has been linked to pityriasis rosea.
Much remains to be learned about the pathogenic role of [beta]-herpesviruses (cytomegalovirus [CMV], human herpesvirus 6 variants A and B [HHV-6A and HHV-6B], and human herpesvirus 7 [HHV-7]) in immune-compromised children.
Biologic properties of human herpesvirus 7 strain SB.
Human herpesvirus 7 exhibits tropism that is similar to that of HHV-6, and HHV-7 also infects humans in early childhood and persists subsequently as a latent infection.
Reactivation of human herpesvirus 6 by infection of human herpesvirus 7. J Med Virol.
Human herpesvirus 7 is a T-lymphotropic virus and is related to, but significantly different from, human herpesvirus 6 and human cytomegalovirus.
Invasion by human herpesvirus 6 and human herpesvirus 7 of the central nervous system in patients with neurological signs and symptoms.
Human herpesvirus 7 is a constitutive inhabitant of adult human saliva.
Detection of human herpesvirus 6 and human herpesvirus 7 in the submandibular gland, parotid gland, and lip salivary gland by PCR.
More than 100 additional HHV-6 strains have been isolated from PBMCs of children with subitum or febrile syndromes (8), from cell-free saliva of healthy or HIV-infected patients (9,10), from PBMCs of patients with chronic fatigue syndrome (CFS) (11), and from PBMCs of healthy adults--these PBMCs were cultivated for human herpesvirus 7 (HHV-7) isolation (12).
Determination and analysis of the complete nucleotide sequence of human herpesvirus 7. J Virol 1996;70:5975-89.