human fibrinogen

hu·man fi·brin·o·gen

fibrinogen prepared from normal human plasma; a coagulant (clotting factor), used as an adjunct in the management of acute, congenital, or acquired chronic hypofibrinogenemia.
Farlex Partner Medical Dictionary © Farlex 2012

hu·man fi·brin·o·gen

(hyūmăn fī-brinō-jen)
Fibrinogen prepared from normal human plasma; coagulant (clotting factor), used as an adjunct in management of acute, congenital, or acquired chronic hypofibrinogenemia.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
The fibrinogenolytic activity was evaluated by incubating 20 [micro]g of human fibrinogen (Sigma Aldrich) with 5 [micro]g of the crude extract for 15, 30, 45, 60 and 120 min.
It consists of an equine collagen patch coated with fibrin glue components: human fibrinogen and human thrombin.
Gelrin is a biodegradable hydrogel based on polyethylene glycol diacrylate and denatured human fibrinogen originally developed at the Technion - Israel Institute of Technology.
Human fibrinogen is a soluble, 46 nm long, 340 kDa glycoprotein and is the third most prevalent protein found in blood plasma, circulating at 6-12 [micro]M [5].
Each component of EVARREST--a Oxidized Regenerated Cellulose (ORC) underlying layer, nonwoven polyglactin 910 fibers needle-punched into the underlying ORC layer to provide increased surface area and mechanical strength and a surface layer of lyophilized human fibrinogen and human thrombin--plays an active role in the hemostasis process.
The reagents used in this study are fibrinogen fluorescence dye (Alexa Fluor 488 human fibrinogen conjugates (F-13191) purchased from Molecular Probes and prepared as per manufacturer's instructions.
Lyophilized human fibrinogen (Sigma-Aldrich, Prague, Czech Republic) (4mg/mL) was dissolved in phosphate buffer saline (PBS; 137 M NaCl, 2.7 mM KCl, 8 mM [Na.sub.2]HP[O.sub.4] x 12[H.sub.2]O,1.5 mM K[H.sub.2]P[O.sub.4], and pH 7.4).
(19.) Dhall TZ, Bryce WA, Dhall DP: Effects of dextran on the molecular structure and tensile behavior of human fibrinogen. Thromb Haemost 1976; 35:737-745.
The different protein coating solutions consisted of 2 mg/ml human albumin (Pharmacia & Upjohn AB, Stockholm, Sweden), 2 mg/ml human fibrinogen (American Diagnostica Inc., Greenwich, Connecticut, USA), 10 pg/ml human fibronectin (Roche Diagnostics, Mannheim, Germany) or 0.1 mg/ml collagen S from calf skin (Roche Diagnostics) combined with 2 pg/ml horse tendon collagen (Biopool International, Ventura, California, USA).
Plasminogen-free unfractionated human fibrinogen was obtained from Calbiochem.

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