Contract award notice: : fn motol - anti-inhibitory complex of coagulation factors, Human fibrinogen
Gelrin is a biodegradable hydrogel based on polyethylene glycol diacrylate and denatured human fibrinogen
originally developed at the Technion - Israel Institute of Technology.
and Rat type IV Collagen were purchased from Sigma Chemical (St.
Each component of EVARREST--a Oxidized Regenerated Cellulose (ORC) underlying layer, nonwoven polyglactin 910 fibers needle-punched into the underlying ORC layer to provide increased surface area and mechanical strength and a surface layer of lyophilized human fibrinogen
and human thrombin--plays an active role in the hemostasis process.
Dhall TZ, Bryce WA, Dhall DP: Effects of dextran on the molecular structure and tensile behavior of human fibrinogen
The different protein coating solutions consisted of 2 mg/ml human albumin (Pharmacia & Upjohn AB, Stockholm, Sweden), 2 mg/ml human fibrinogen
(American Diagnostica Inc.
Plasminogen-free unfractionated human fibrinogen
was obtained from Calbiochem.
Pharming is developing recombinant human fibrinogen
as a replacement therapy for patients with genetic and acquired deficiencies of fibrinogen.
Baxter's Tisseel VH Fibrin Sealant has the maximum concentration of human fibrinogen
to stimulate this natural physiologic clotting process.
Pharming has obtained patents and licenses on various products and technologies, including the production and purification of recombinant human fibrinogen
and recombinant tissue sealant compositions.
Gamma-chain dysfibrinogenemias: molecular structure-function relationships of naturally occurring mutations in the gamma chain of human fibrinogen
Latex particles, coated with antibodies to human fibrinogen
fragments D and E, are mixed with patient serum (or urine).