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We chose the human IgG expression system to add the human IgG constant region to the CSLEX-1 binding site, thus expecting to eliminate human antimouse antibody (HAMA) reactions causing a pseudopositive diagnosis of the HAMA-positive samples.
41) Human antimouse antibody (HAMA) interference is a special case of heterophilic antibody interference, where the HAMA interacts with murine antibodies.
of a human antimouse antibody (HAMA) causing interference within a CsA immunoassay illustrates the insidious nature of this type of interference.

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