homozygous


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ho·mo·zy·gous

(hō'mō-zī'gŭs),
Having identical alleles at one or more loci.

homozygous

(hō′mō-zī′gəs, -mə-, hŏm′ə-)
adj.
Having the same alleles at a particular gene locus on homologous chromosomes.

ho′mo·zy·gos′i·ty (-gŏs′ĭ-tē) n.
ho′mo·zy′gous·ly adv.

homozygous

[hō′məzī′gəs]
Etymology: Gk, homos + zygon, yoke
having two identical alleles at corresponding loci on homologous chromosomes. An individual who is homozygous for a trait has inherited from each parent one allele for that trait. A person who is homozygous for a genetic disease caused by a pair of recessive alleles, such as sickle cell anemia, manifests the disorder. All of his or her offspring will inherit the allele for the disease. Compare heterozygous.

ho·mo·zy·gous

(hō'mō-zī'gŭs)
Having identical genes at one or more loci.

homozygous

Having identical gene pairs (ALLELES) at corresponding positions (loci) on the chromosome pairs. People who are homozygous for a quality or condition will always manifest it.

Homozygous

Identical genes controlling a specified inherited trait.

homozygous

expression of inheritance of genetic disease, where the individual inherits the causative gene from both parents and expresses overt disease (see heterozygous)

ho·mo·zy·gous

(hō'mō-zī'gŭs)
Having identical alleles at one or more loci.

homozygous (hō´mōzī´gus),

adj a term indicating that genes lying at equivalent loci on chromosome pairs are the same.

homozygous

having the characteristic of homozygosity.
References in periodicals archive ?
sup][6] first reported two siblings from a consanguineous family carrying a homozygous missense mutation (G1709R) and presented with ptosis, mild facial and limb-girdle muscles weakness.
No evidence of publication bias was found in case of heterozygous Arg/Gly, homozygous Glu, and homozygous Gly.
2) with homozygous b-thal was identified in 30% cases of our cohort.
Karyotype analysis of homozygous [alpha]GT KO fibroblasts was performed by GenDix, Inc (Seoul, Korea), a commercial provider of karyotyping.
The report reviews pipeline therapeutics for Homozygous Familial Hypercholesterolemia (HoFH) by companies and universities/research institutes based on information derived from company and industry-specific sources
While in DDP, daily milk yield rates were higher in both AB and BB b-LG genotyped animals as compared to the homozygous AA.
In the major depressive disorder group, the homozygous wild type (GG) had a single 530-bp DNA fragment, homozygous mutant type (CC) had two DNA fragments with sizes of 342 bp and 154 bp (homozygous mutant type had another fragment that could not be observed on the gel), and heterozygous type (GC) had three DNA fragments of 530 bp, 342 bp, and 154bp (Figure 2).
At each individual locus, all 3 possible genotypes (ie, homozygous wild type, heterozygous, and homozygous mutant) were detected.
i]/(k)}, (i [member of] S, k [member of] V), were estimated using the expected homozygous and expected heterozygous sites:
Patients with one or two copies of the Asp40 allele and those who were homozygous for the Asn40 allele were randomized to naltrexone 50 mg a day or placebo and the primary outcome measured was relapse to heavy drinking during treatment.
These individuals showed a singular band of greater than 350 bp and they were homozygous for that.
The better hybridized probe then leads to stronger signal generation, and allows direct determination of heterozygous or either homozygous state by analysis of which fluorescent label appears as the reaction proceeds.