homozygous


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ho·mo·zy·gous

(hō'mō-zī'gŭs),
Having identical alleles at one or more loci.

homozygous

(hō′mō-zī′gəs, -mə-, hŏm′ə-)
adj.
Having the same alleles at a particular gene locus on homologous chromosomes.

ho′mo·zy·gos′i·ty (-gŏs′ĭ-tē) n.
ho′mo·zy′gous·ly adv.

ho·mo·zy·gous

(hō'mō-zī'gŭs)
Having identical genes at one or more loci.

homozygous

Having identical gene pairs (ALLELES) at corresponding positions (loci) on the chromosome pairs. People who are homozygous for a quality or condition will always manifest it.

Homozygous

Identical genes controlling a specified inherited trait.

ho·mo·zy·gous

(hō'mō-zī'gŭs)
Having identical alleles at one or more loci.
References in periodicals archive ?
Homozygous [K.sub.ATP] channel gene mutations are the most common cause of severe, diazoxide unresponsive HH which often requires pancreatectomy (3,13).
Of the 25 laboratories responding, 23 had participated in the 2015 MGL2 SCA challenge; 15 had reported a homozygous result, 7 had reported a heterozygous result, and 1 had not reported a numeric result (result reported as normal).
The authors reported to have found the homozygous AA genotype of MnSOD Valine16Alanine (Val16Ala) to be significantly more prevalent in the study group than in the control group (93% vs 13%).
The mean weights of piglets at postnatal day 50 were examined in homozygous and/or heterozygous piglets with different SLA class II haplotypes (Supplementary Table S1).
First, the patient has compound heterozygous variants in a gene associated with autosomal recessive epilepsy and shares many of the clinical features observed for the previously reported patients with homozygous CACNA2D2 mutations (Figures 1(c) and 1(d), Table 1).
In exon 3, we found a novel homozygous frameshift mutation (c.423_424insG, p.Gly143fs), resulting in a completely different translation from the original.
Variants in exonic regions of zinc transport genes were filtered by ExAC frequency and CADD score using "R" to identify rare, predicted deleterious variants present in a homozygous form (see sup materials).
We identified a novel homozygous missense mutation (c.5302G>C) in exon 31 of AGRN leading to the substitution of alanine to proline in the C-terminal LG2 domain of agrin (p.
Conclusion: Heterozygous Arg/Gly, homozygous Gly/Gly and Gly Allele were found to be significantly associated with nocturnal asthma.
The deletion that found in parents have been accepted as a disease-causing mutation and we think the deceased child that diagnosed with ZS had this deletion in homozygous form.