homozygous


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ho·mo·zy·gous

(hō'mō-zī'gŭs),
Having identical alleles at one or more loci.

homozygous

(hō′mō-zī′gəs, -mə-, hŏm′ə-)
adj.
Having the same alleles at a particular gene locus on homologous chromosomes.

ho′mo·zy·gos′i·ty (-gŏs′ĭ-tē) n.
ho′mo·zy′gous·ly adv.

homozygous

[hō′məzī′gəs]
Etymology: Gk, homos + zygon, yoke
having two identical alleles at corresponding loci on homologous chromosomes. An individual who is homozygous for a trait has inherited from each parent one allele for that trait. A person who is homozygous for a genetic disease caused by a pair of recessive alleles, such as sickle cell anemia, manifests the disorder. All of his or her offspring will inherit the allele for the disease. Compare heterozygous.

ho·mo·zy·gous

(hō'mō-zī'gŭs)
Having identical genes at one or more loci.

homozygous

Having identical gene pairs (ALLELES) at corresponding positions (loci) on the chromosome pairs. People who are homozygous for a quality or condition will always manifest it.

Homozygous

Identical genes controlling a specified inherited trait.

homozygous

expression of inheritance of genetic disease, where the individual inherits the causative gene from both parents and expresses overt disease (see heterozygous)

ho·mo·zy·gous

(hō'mō-zī'gŭs)
Having identical alleles at one or more loci.

homozygous (hō´mōzī´gus),

adj a term indicating that genes lying at equivalent loci on chromosome pairs are the same.

homozygous

having the characteristic of homozygosity.
References in periodicals archive ?
For this review a computer search of the Canterbury Health Laboratory thalassaemia database was run using a diagnosis of homozygous Hb E as the search criteria.
Although the obstacles to creating a public homozygous stem cell bank, which we discuss later, are formidable, creating such a bank is, we believe, technically feasible.
2] gene, we can expect that homozygous plants will fluoresce twice as much as heterozygous plants," says Vandemark.
Of the uninfected blood donors, 104 (99%) were homozygous for the wild type, and 1 (0.
This suggests that bucindolol may have clinically important anti-ventricular arrhythmic effects in the roughly 50% of patients who have the beta-1 389 arginine homozygous genotype, and I believe that further study of bucindolol in additional clinical trials is warranted.
Today laboratories have the ability to select methodologies that show which hemoglobin variants may be present and to determine whether the sample is heterozygous or homozygous.
Fetuses with homozygous [alpha]-thalassemia usually die in utero Even if born alive, the prognosis is extremely poor, as almost all of them die within a few hours of birth.
Our study showed a higher frequency of JAK2 V617F mutation in homozygous state in patients with PV (82%) and ET (71%) than that reported from the West (PV, 25-30; ET, 2%) (5-7).
0 [micro]g/dL) found that the ALAD polymorphism did not change the association between blood lead and hypertension at occupational exposure levels compared with ALAD1 homozygous carriers (Lee et al.
Fifty-four patients with premature cardiovascular disease (55 years and under for men, 65 years and under for women) who were homozygous for the methylenetetrahydrofolate reductase (MTHFR) 677C[right arrow]T polymorphism (i.
The purpose of this article was to report the genotype-phenotype correlations for a 9-year, 11-month-old boy with homozygous ENAM mutation (c.