homozygote


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

homozygote

 [ho″mo-zi´gōt]
an individual exhibiting homozygosity.

ho·mo·zy·gote

(hō'mō-zī'gōt),
A homozygous individual.
[homo- + G. zygōtos, yoke]

homozygote

(hō′mō-zī′gōt′, -mə-, hŏm′ə-)
n.
An organism that has the same alleles at a particular gene locus on homologous chromosomes.

homozygote

[hō′məzī′gōt]
Etymology: Gk, homos, same, zygon, yoke
an organism whose somatic cells have identical genes on the same locus on one of the chromosome pairs.

ho·mo·zy·gote

(hō'mō-zī'gōt)
A homozygous individual.
[homo- + G. zygōtos, yoke]

homozygote

an individual containing two identical forms of the same GENE in all DIPLOID (1) cells that is capable of pure breeding. Thus if gene A has two alleles, A 1 and A 2, two homozygous types are possible: A1/A1 and A 2/A2. Compare HETEROZYGOTE.

homozygote

an animal exhibiting homozygosity.
References in periodicals archive ?
Such procedure could save time and cost for the production of homozygote KO animals by breeding, especially in species that requires substantial length of gestation.
In particular, MTHFR A1298C homozygote mutation has been shown to lead to cerebrovascular thrombosis and stroke in children.
2000) studied a population of Northern European white and concluded a 4-10 fold lower risk of asthma for GSTP1 Val/Val homozygotes which corresponds to our own findings.
Those with MT1A (rs8052394) heterozygote GA and homozygote variant GG genotypes had lower hair mercury levels than did those with homozygote AA genotype (Table 5; see Supplemental Material, Figure 1d).
In our study, 5 patients were homozygote for HFE mutations, but only one for the C282Y.
People with the Trp460 allele has a lowered BP to greater levels in response to diuretic therapy and are more responsive to sodium challenges (25) compared with [alpha]-adducin Gly460Gly homozygotes.
11) Mean 24 h intragastric pH measured at intervals of 2 h in healthy Japanese normal homozygotes, heterozygotes and mutant homozygotes was 2.
Although most abnormal [beta]-chain variants show some level of functional abnormality, they reduce symptoms compared to a sickle cell homozygote because they do not polymerize like HbS and actually interfere with the polymerization of HbS molecules.
One F1 albino male was crossed with three different homozygote wild-type females and all F2 offspring had a wild-type phenotype.
Polymorphism in intron 4 of HFE may cause overestimation of C282Y homozygote prevalence in haemochromatosis [letter].
4) 0 Expected phenotype(b) Extensive metabolizer Homozygote 29 (70.