homozygosity


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homozygosity

 [ho″mo-zi-gos´ĭ-te]
the state of having identical alleles in regard to a given character or characters. adj., adj homozy´gous.

ho·mo·zy·gos·i·ty

, homozygosis (hō'mō-zī-gos'i-tē, -zī-gō'sis),
The state of being homozygous.
[homo- + G. zygon, yoke]

ho·mo·zy·gos·i·ty

, homozygosis (hō'mō-zī-gos'i-tē, -zī-gō'sis)
The state of being homozygous.
[homo- + G. zygon, yoke]

homozygosity

the state of having identical alleles in regard to a given character or characters.
References in periodicals archive ?
Homozygosity for a missense mutation in SERPINH1, which encodes the collagen chaperone protein HSP47, results in severe recessive osteogenesis imperfecta.
In addition, most of these cases were shown to be caused by inbreeding within a family that carries a familial translocation, and were discovered following detection of an existing familial rearrangement rather than any specific characteristic for the homozygosity (16).
Patients harboring the CC genotype in VDR rs2228570 were more often dyslipidemic compared to subjects showing minor homozygosity (the TT genotype) (46.
5 haplotype homozygosity conferred the highest risk for CD and was associated with the earliest onset [31].
Relation of EHTN transmission with the homozygosity and heterozygosity was plotted against the participants in the pedigree trees for interpretation using software Cyrillic version 2.
This is particularly important in the context of genetic disease, since runs of homozygosity (ROH) increase the incidence of recessive mutations being expressed as a disease phenotype.
Frequency of germline genomic homozygosity associated with cancer case.
In a secondary analysis of a study involving 552 hypothyroid patients randomized to LT4 or LT4 / LT3, the prevalence of Thr92Ala homozygosity was 16%, and psychological well-being in patients with the deiodinase 2 polymorphism improved significantly more on combination therapy than with LT4 alone (J.
In a secondary analysis of a study involving 552 hypothyroid patients randomized to LT4 or LT4/LT3, the prevalence of Thr92Ala homozygosity was 16%, and psychological well-being in patients with the deiodinase 2 polymorphism improved significantly more on combination therapy than with LT4 alone (J.
Homozygosity mapping of a gene for arterial tortuosity syndrome to chromosome 20q13.