homotetramer

homotetramer

(hō″mō-te′tră-mĕr) [ homo- + tetramer]
A structure such as a molecule or a polymer made of four identical parts.
References in periodicals archive ?
The TRPV1 channel acts as a homotetramer and heterotetramer with other TRP channel subunits [17].
Specifically, 5F11 scFv fragments were fused with streptavidin to form a homotetramer that displayed an increased avidity to GD2; [sup.111]In-DOTA conjugated to biotin was used as the ligand ([sup.111]In-DOTA-biotin).
However, the homotetramer LDH-C4 was previously only detected in testis and spermatozoa and not in any other tissues or cells (Goldberg, 1964, 1975, 1984; Coonrod et al., 2006).
The second revised phytase, the 3-phytase B (PDB ID: 1QFX), initially corresponds to a homodimer (Chains A and B) which, thanks to its crystallographic symmetry, generates a homotetramer from two dimers.
It is a homotetramer (96 KDa) containing one manganese atom per subunit that cycles from [Mn.sup.3+] to [Mn.sup.2+] and back to [Mn.sup.3+] during the two-step dismutation of superoxide.
Reversible inactivation of an intracellular uricase from Bacillusfastidiosus via dissociation of homotetramer into homodimers in solutions of low ionic strength, Biosci.
It was shown to be a 96 kDa homotetramer and located exclusively in the mitochondrial matrix, a prime site of superoxide radical production (Halliwell and Gutteridge, 1999).
neapolitana existed both as homodimer as well as homotetramer have been produced under mesophilic fermentation conditions with a maximal activity at 97C.
FKBP12.6 is anchored in the corner of the RyR2 homotetramer, forming a structural complex that stabilizes and regulates the closed state of these channels, preventing intracellular [Ca.sup.2+] leak and arrhythmogenesis (5).
The NarL protein (in the asymmetric unit) is a homotetramer containing 4 identical subunits having their independent active sites each for subunits A, B, C, and D, respectively.
also reported that Kir2.6 forms functional homotetramer and heterotetramer with Kir2.1, another Kir channel in the skeletal muscle.