Wang et al., "Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine
lactone synthase as druggable target," Scientific Reports, vol.
Davis et al., "The Fe(III) and Ga(III) coordination chemistry of 3-(1-hydroxymethylidene) and 3-(1-hydroxydecylidene)-5-(2-hydroxyethyl)pyrrolidine-2,4-dione: novel tetramic acid degradation products of homoserine
lactone bacterial quorum sensing molecules," Journal of Inorganic Biochemistry, vol.
Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine
Lysine was the first amino acid that was produced with the help of mutant strains that require homoserine
for hyper production in industry (Shah and Khan, 2008).Selection of substrate is as important as microbe selectionfor fermentation (Kothari, 2009).
The Pseudomonas autoinducer N-(3-oxododecanoyl) homoserine
lactone induces cyclo-oxygenase-2 and prostaglandin E2 production in human lung fibroblasts: Implications for inflammation.
Identification, cloning and lactonase activity of recombinant protein of N-acyl homoserine
lactonase (AiiA) from Bacillus thuringiensis 147-115-16 strain
Lucas et al., "Salmonella enterica serovar typhimurium can detect acyl homoserine
lactone production by Yersinia enterocolitica in mice," Journal of Bacteriology, vol.
Gram-negative bacteria utilize the autoinducer-1 involving N-acyl homoserine
lactone (AHL) and Gram-positive bacteria utilize the posttranslationally modified oligopeptide signaling molecules classified as autoinducer-2 [1, 4].
Feng, "Ecological roles and release patterns of acylated homoserine
lactones in Pseudomonas sp.
In general, Gram-negative bacteria use acylated homoserine
lactose as autoinducers or to communicate, and Gran-positive bacteria use processed oligopeptides to communicate .
stewartii uses 3oxohexanoyl acyl carrier protein and SAdenosylL Methionine (SAM) as substrates to make 3oxohexanoyl homoserine
lactone (AHL) autoinducers.
The aim of the study was to synthesize a fluorescent probe to mark a quorum sensing chemical (i.e., 3-oxododecanoyl homoserine
lactone) bound to a proteic transcriptional modulator present in some bacteria, which would allow for the bioorthogonal labeling of this protein .