XJ12B and Bacillus pumilus (11, 12), N-acyl homoserine
lactonases from Bacillus species, B.
5, (1 mM) Homoserine
400 L/ 20mL, (1 mM) threonine 500 L/ 20mL, (10 mM) 2-(aminoethyl) L- cysteine (AEC) 200 L/ 20mL.
Sequences analysis of aiiA genes using BLAST-X showed that protein encoding by aiiA gene of BKS-1 isolate had 99% similarity with group protein of N-acyl homoserine
lactonase from B.
Conjugates of acyl homoserine
lactone and catalase a from pseudomonas aeruginosa .
Acylases are known to be capable of cleaving the acyl bonds and releasing a homoserine
lactone ring (Lin et al.
In general, Gram-negative bacteria use acylated homoserine
lactose as autoinducers or to communicate, and Gran-positive bacteria use processed oligopeptides to communicate .
stewartii uses 3oxohexanoyl acyl carrier protein and SAdenosylL Methionine (SAM) as substrates to make 3oxohexanoyl homoserine
lactone (AHL) autoinducers.
lactone) bound to a proteic transcriptional modulator present in some bacteria, which would allow for the bioorthogonal labeling of this protein .
This phenomenon involves the process of "quorum sensing," that is, the communication between microorganisms by specific ligands such as homoserine
lactones, but also the creation of ecological niches for beneficial microbes by the Hydra epithelium.
Plants secrete substances that mimic bacterial N-acyl homoserine
lactone signal activities and affect population density-dependent behaviors in associated bacteria.
aeruginosa autoinducer 3O-C12 homoserine
lactone provokes hyperinflammatory responses from cystic fibrosis airway epithelial cells.
For example, red algae secrete halogenated furanones and enones that act as antagonists of acylated homoserine
lactone signaling molecules present in biofilms.