homoserine


Also found in: Encyclopedia, Wikipedia.

ho·mo·ser·ine

(hō'mō-ser'ēn),
Amino-4-hydroxybutyric acid; a hydroxyamino acid differing from serine in the possession of an additional CH2 group. An intermediate in the biosynthesis of cystathionine, threonine, and methionine.
Farlex Partner Medical Dictionary © Farlex 2012

ho·mo·ser·ine

(hō'mō-ser'ēn)
A hydroxyamino acid differing from serine in the possession of an additional CH2 group; formed in the conversion of l-methionine to l-cysteine.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Wang et al., "Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target," Scientific Reports, vol.
Davis et al., "The Fe(III) and Ga(III) coordination chemistry of 3-(1-hydroxymethylidene) and 3-(1-hydroxydecylidene)-5-(2-hydroxyethyl)pyrrolidine-2,4-dione: novel tetramic acid degradation products of homoserine lactone bacterial quorum sensing molecules," Journal of Inorganic Biochemistry, vol.
Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine lactonase.
Lysine was the first amino acid that was produced with the help of mutant strains that require homoserine for hyper production in industry (Shah and Khan, 2008).Selection of substrate is as important as microbe selectionfor fermentation (Kothari, 2009).
The Pseudomonas autoinducer N-(3-oxododecanoyl) homoserine lactone induces cyclo-oxygenase-2 and prostaglandin E2 production in human lung fibroblasts: Implications for inflammation.
Identification, cloning and lactonase activity of recombinant protein of N-acyl homoserine lactonase (AiiA) from Bacillus thuringiensis 147-115-16 strain
Lucas et al., "Salmonella enterica serovar typhimurium can detect acyl homoserine lactone production by Yersinia enterocolitica in mice," Journal of Bacteriology, vol.
Gram-negative bacteria utilize the autoinducer-1 involving N-acyl homoserine lactone (AHL) and Gram-positive bacteria utilize the posttranslationally modified oligopeptide signaling molecules classified as autoinducer-2 [1, 4].
In general, Gram-negative bacteria use acylated homoserine lactose as autoinducers or to communicate, and Gran-positive bacteria use processed oligopeptides to communicate [18].
stewartii uses 3oxohexanoyl acyl carrier protein and SAdenosylL Methionine (SAM) as substrates to make 3oxohexanoyl homoserine lactone (AHL) autoinducers.
The aim of the study was to synthesize a fluorescent probe to mark a quorum sensing chemical (i.e., 3-oxododecanoyl homoserine lactone) bound to a proteic transcriptional modulator present in some bacteria, which would allow for the bioorthogonal labeling of this protein [50].