homoprotocatechuic acid

ho·mo·pro·to·cat·e·chu·ic ac·id

(hō'mō-prō'tō-kat'ĕ-chū'ik as'id),
(3,4-dihydroxyphenyl)acetic acid; an isomer of homogentisic acid found in urine; a degradation product of l-tyrosine, l-dopa, and hydroxytyramine.
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Five other metabolites derived from verbascoside and isoverbascoside were also found in plasma, namely hydroxytyrosol, caffeic acid, ferulic acid, ferulic acid glucuronide, and homoprotocatechuic acid, together with another eight phenolic compounds.
Five metabolites deriving from verbascoside and isoverbascoside were also found in plasma due to the metabolism of the rats, namely hydroxytyrosol, caffeic acid, ferulic acid, ferulic acid glucuronide, and homoprotocatechuic acid. Polyphenol glycosides are absorbed mainly through the gut barrier after deglycosylation by the action of lactase phloridzin hydrolase in the brush border of the small-intestine epithelial cells, cytosolic [beta]-glucosidase within the epithelial cells, or colonic microbiota in the large intestine (Crozier et al.
Homoprotocatechuic acid has been also described as a metabolite of caffeic acid (Gonthier et al.