For phylogeny four closest homologous proteins
of TGF-[beta] superfamily were selected i.
The RAS proto-oncogenes (ERAS, KRAS, and NRAS) encode HRAS, KRAS 4A, KRAS 4B, and NRAS, 4 distinct but closely related and highly homologous proteins
Many foods share homologous proteins
therefore sensitization to one food can result in positive tests or clinical reactivity to related foods developing multiple foods sensitization sometimes leading to the development of allergy symptoms.
Although many of the mechanisms that govern membrane organization are increasingly well understood, such as lipid rafts or protein-anchoring to the cortical cytoskeleton, these mechanisms are not sufficiently specific to account for the partitioning of closely homologous proteins
in separate membrane domains.
Antibodies formed to species-specific protein components typically bind only to the proteins particular to that species, but homologous proteins
(with similar structures) may also exist in related or unrelated species.
The heat shock protein 70 family: Highly homologous proteins
with overlapping and distinct functions.
We used a BLASTP search to determine the similarity of predicted R1101 proteins to homologous proteins
Indel's core antimicrobial targeting technology identifies and targets discrete amino acid insertion or deletion differences ("indels") between essential homologous proteins
that are evolutionarily conserved across the pathogen (bacteria) and humans.
Conserved homologous proteins
shared by pollens and foods likely account for this cross-reactivity.
If therapeutic is in a family of homologous proteins
, assess antibody cross-reactivity with all family members
5) The pollens and foods involved usually are not botanically related but contain homologous proteins
, as there are shared binding sites (epitopes) in the structures of pollen and food allergens.
This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins
or protein complexes.