homeobox genes

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homeobox genes

A highly CONSERVED family of genes, found in a large range of different species, including insects. Homeobox genes are expressed early in embryonic development and are the determinants of body shape. These genes divide the early embryo into fields of cells each with the potentiality to develop into a particular part such as an arm, leg, tissue or organ. This is the key to the long-unexplained problem of how bodily configuration is determined by genetics. Mutations in homeobox genes cause severe bodily defects such as PHOCOMELIA.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

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Cappechi plans to disrupt several other of the 40 or so homeobox genes in mice in hopes of elucidating their function.

Of mice and men: sharing locator genes

Control of neural development and function in a thermoregulatory network by the LIM homeobox gene lin-11.

Frog Lim-1-like Protein Is Expressed Predominantly in the Nervous Tissue, Gonads, and Early Embryos of the Bivalve Mollusc Mytilus galloprovincialis

HOM/HOX homeobox genes are present in hydra (Chlorohydra viridissima) and are differentially expressed during regeneration.

Evolution of head development

elegans LIM homeobox genes leads to another interesting point: the expression of most, if not all of these genes is maintained in neural tissues throughout adulthood.

A common theme for LIM homeobox gene function across phylogeny?

Identification of a retinoic acid responsive enhancer 3[prime] of the murine homeobox gene Hox 1.6.

Exogenous retinoic acid during gastrulation induces cartilaginous and other craniofacial defects in Fundulus heteroclitus

We have chosen to study homeobox genes in the Anthozoa that we might better understand the ancestral function of these genes in the Cnidaria and in the Eumetazoa.

Homeoboxes in sea anemones (Cnidaria; Anthozoa): a PCR-based survey of Nematostella vectensis and Metridium senile

Machida, "The ASYMMETRICLEAVES2 gene of Arabidopsis thaliana regulates formation of a symmetric lamina, establishment of venation and repression of meristem-related homeobox genes in leaves," Development, vol.

The YABBY Genes of Leaf and Leaf-Like Organ Polarity in Leafless Plant Monotropa hypopitys

Bechi et al., "Expression of HOX homeobox genes in the adult human colonic mucosa (and colorectal cancer?)," International Journal of Molecular Medicine, vol.

Role of HOX Genes in Stem Cell Differentiation and Cancer

Mutual antagonism of the paired-type homeobox genes, vsx2 and dmbxl, regulates retinal progenitor cell cycle exit upstream of ccnd1 expression.

Early transcriptional responses during heat Stress in the Coral Acropora hyacinthus

The sonic hedgehog, homeobox gene Pdx1, and Notch signaling systems are effective in the development of the pancreas (43, 44).

Development of Liver and Pancreas

Boncinelli, "Homeobox genes and cancer," Experimental Cell Research, vol.

HOXB9 Expression Correlates with Histological Grade and Prognosis in LSCC

Homeobox genes are involved in body plan formation and in the regulation of many developmental processes in bilateria.

Hox, Parahox, EHGbox, and NK genes in bivalve molluscs: evolutionary implications