Hex homeobox gene
controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development.
Genes of the NK2 class have a distinctive homeobox and encode proteins that have a tyrosine at homeodomain position 54, and the Tlx family of homeobox genes
is distinguished by a Thr in position 47 of the homeodomain.
Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene
The fact that each of the fields expresses different combinations of patterning homeobox genes
supports this theory
1) is a homeobox gene
with mutations that effect second premolars and third molars with an association for cleft lip and/or palate and Witkop syndrome (Zhang et al.
Expression pattern of KN-1 type tobacco homeobox genes
Vertebrate homologs of tinman and bagpipe: roles of the homeobox genes
in cardiovascular development.
Members of the Antennapedia class of homeobox genes
, known as Hox genes, are believed to be pivotal in regulating vertebrate craniofacial development and controlling morphogenesis and the growth of the proximal-distal axis.
Missense mutations in R31 have been found in the human homeobox genes
PITX2, MSXI, MSX2, LMX1B, and HOXD13 and are associated with 5 different developmental diseases: iridogoniodysgenesis syndrome, tooth agenesis, enlarged parietal foramina, nail-patella syndrome, and several digital anomalies, respectively (18, 19).
Role of the Dlx homeobox genes
in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches.
Although researchers know that alcohol can affect the expression of some genes, it is uncertain whether these include homeobox genes
Such products might be extracellular signaling molecules, such as growth factors or differentiation signals, but also transcriptional regulators, for example, a retinoic acid receptor acting on homeobox genes
in a developing vertebrate limb.