homeobox gene


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to homeobox gene: Hox gene

homeobox gene

n.
One of a group of genes with a characteristic sequence of nucleotides coding an amino acid sequence that functions in binding to DNA. Homeobox genes are involved in the formation of bodily segmentation during embryologic development.

homeobox gene

Any transcription factor that regulates the growth, differentiation, replication, and movement of cells in the body. These genes influence both normal and abnormal embyological development and the development or suppression of malignant tumors.
See also: gene
References in periodicals archive ?
Sauvageau et al., "Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis," Blood, vol.
The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis.
A Mox homeobox gene in the gastropod mollusc Haliotis rufescens is differentially expressed during larval morphogenesis and metamorphosis.
Zhou, "A WUSCHELLIKE HOMEOBOX gene represses a YABBY gene expression required for rice leaf development," Plant Physiology, vol.
Expressions of Msx and Dlx homeobox genes have been studied by Ruhin-Poncet et al.
Hence, disruption of homeobox gene expression, a downstream target of the AHR/TCDD axis, is potentially a major component of the inhibition of cardiomyocyte function by TCDD.
Negative auto regulation of the Arabidopsis homeobox gene ATHB-2.
Members of the homeobox gene family are among the important factors involved in craniofacial development.
Benameur et al., "The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells," Oncogene, vol.
MSX1 (OMIM 142983: 4p16.3-p16.1) is a homeobox gene with mutations that effect second premolars and third molars with an association for cleft lip and/or palate and Witkop syndrome (Zhang et al., 2005; Fleischmannova et al., 2008; Kavitha et al., 2010; Pani, 2011).
The rough sheath2 gene negatively regulates homeobox gene expression during maize leaf development.