The company stated that hydrocodone bitartrate and homatropine
methylbromide oral solution (syrup), 5 mg/1.5 mg per 5 ml is indicated for the symptomatic relief of cough in adults and children six years of age and older.
The purpose of this study was to demonstrate the effect on axial parameters of the eye, after instillation of 1% Tropicamide eye drop and 2% Homatropine
Commenting on the approval, Michael Reicher, president & CEO, stated that "the approval for Hydrocodone Bitartrate and Homatropine
Methylbromide Syrup expands the company's liquid line of products and extends the company's line of cough and cold medications.
However, the consequence was that we will have missed any shorter-term effects of atropine, should they have occurred, for example, equivalent to the observation that homatropine
can cause choroidal thickening 1 hour after instillation .
produces cycloplegia in 20-30 minutes and recovery of accommodation in 24 hours
She was started on ointment acyclovir, guttae loteprednol, homatropine
, and tear supplements.
, choroidal thickness is observed for the group where 2% homatropine
Other key products in the Wockhardt USA product line include azithromycin tablets, divaloproex ER tablets, enalapril tablets, metoprolol succinate ER tablets, nicardipine injection, ropinirole HCI tablets, ceftriaxone injection, tamsulosin capsules, hydrocodone and homatropine
syrup, megestrol acetate oral suspension, nystatin oral suspension, and phenytoin oral suspension.
Traditional cycloplegics included atropine (eg, 0.5% or 1% eye drops used BDS, or 1% ointment applied prior to pressure patching) and homatropine
(2% or 5% administered at least BDS).
Only seven prescription hydrocodone-containing cough suppressants are FDA approved: Hycodan (ENDO Pharms), Mycodone (Morton Grove), Tussicaps (Tyco Healthcare), Tussigon (King Pharmaceuticals), Tussionex Pennkinetic (UCB Inc.), Hydrocodone compound (Actavis Mid Atlantic), and Homatropine
methylbromide and hydrocodone bitartrate (Actavis Totowa).
Alongside, supportive therapy like pain medications are given, including topical cycloplegics like atropine or homatropine
to dilate the pupil and thereby stop spasms of the ciliary muscle.