homatropine


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homatropine

 [ho-mat´ro-pēn]
an anticholinergic and antimuscarinic producing sympathetic blockade effects similar to but weaker than those of atropine; the hydrobromide salt is used as a mydriatic and cycloplegic and the methylbromide salt is used as an inhibitor of gastric spasm and secretion.

ho·mat·ro·pine

(hō-mat'rō-pēn),
An anticholinergic, mydriatic, and cycloplegic agent; available as the hydrobromide and the methylbromide.

homatropine

(hō-măt′rō-pēn′)
n.
An anticholinergic drug derived from tropine, C16H21NO3, used in its bromide form to dilate the pupil of the eye and in combination with hydrocodone to prevent overdosage of that drug.

homatropine

A drug used in the form of eyedrops to widen the pupils for ophthalmic examination and temporarily to paralyze the muscles of the iris to assist in the treatment of iris inflammation (anterior UVEITIS).
References in periodicals archive ?
The company stated that hydrocodone bitartrate and homatropine methylbromide oral solution (syrup), 5 mg/1.5 mg per 5 ml is indicated for the symptomatic relief of cough in adults and children six years of age and older.
The purpose of this study was to demonstrate the effect on axial parameters of the eye, after instillation of 1% Tropicamide eye drop and 2% Homatropine eye drop.
Commenting on the approval, Michael Reicher, president & CEO, stated that "the approval for Hydrocodone Bitartrate and Homatropine Methylbromide Syrup expands the company's liquid line of products and extends the company's line of cough and cold medications.
However, the consequence was that we will have missed any shorter-term effects of atropine, should they have occurred, for example, equivalent to the observation that homatropine can cause choroidal thickening 1 hour after instillation [28].
c) Homatropine produces cycloplegia in 20-30 minutes and recovery of accommodation in 24 hours
She was started on ointment acyclovir, guttae loteprednol, homatropine, and tear supplements.
Other key products in the Wockhardt USA product line include azithromycin tablets, divaloproex ER tablets, enalapril tablets, metoprolol succinate ER tablets, nicardipine injection, ropinirole HCI tablets, ceftriaxone injection, tamsulosin capsules, hydrocodone and homatropine syrup, megestrol acetate oral suspension, nystatin oral suspension, and phenytoin oral suspension.
Traditional cycloplegics included atropine (eg, 0.5% or 1% eye drops used BDS, or 1% ointment applied prior to pressure patching) and homatropine (2% or 5% administered at least BDS).
Only seven prescription hydrocodone-containing cough suppressants are FDA approved: Hycodan (ENDO Pharms), Mycodone (Morton Grove), Tussicaps (Tyco Healthcare), Tussigon (King Pharmaceuticals), Tussionex Pennkinetic (UCB Inc.), Hydrocodone compound (Actavis Mid Atlantic), and Homatropine methylbromide and hydrocodone bitartrate (Actavis Totowa).
Alongside, supportive therapy like pain medications are given, including topical cycloplegics like atropine or homatropine to dilate the pupil and thereby stop spasms of the ciliary muscle.