The decrease in endometrial glandular expression of PGRAB protein indicates a decline in PGRAB-mediated progesterone action in endometrial glands from days 14 to 30 of early pregnancy, which could influence secretion of
histotroph.
Proteomic characterization of
histotroph during the preimplantation phase of the estrous cycle in cattle.
Histotroph includes proteins and other molecules secreted into the uterine lumen by uterine epithelia, as well as proteins and other molecules, such as glucose and amino acids, transported into the uterine lumen to support growth and development of the conceptus.
The secretory products of the endometrial glands are known collectively as
histotroph and consist of enzymes, growth factors, cytokines, lymphokines, hormones, transport proteins, and other substances.
