It is an acute, endogenous/soil-borne infection caused by Clostridium chauvoei, a Gram positive, motile, histotoxic
, and sporulating anaerobic bacterial species (USEH et al., 2006a).
hypoxia" is the medical term associated with the disorientating disorder which can put pilots' lives at risk, as well as those of civilians on the ground below.
They cover the pathogenic clostridia, toxins produced by the pathogenic clostridia, clostridial infections of the gastrointestinal system, clostridial histotoxic
infections, and clostridial neurotoxic infections.
Clostridium perfringens is one of the most important food-borne pathogen of humans and animals causing both histotoxic
diseases and intestinal infections (4-7).
On the other hand, the free fatty acid theory proposes that excessive mobilization of free fatty acids leads to severe vasculitis that is secondary to its histotoxic
effects.[sup] CFE can be present without pulmonary effects; potentially due to the fact that smaller globules may traverse the pulmonary microvasculature and reach the systemic circulation; alternatively, CFE may be caused by fat globules via the patent foramen ovale.[sup] Three patients went into a coma shortly after the fracture and remained comatose at the 3-month follow-up.
The alpha toxin is reported as hemolytic, necrotic and histotoxic
(Quinn et al., 2005).
This toxin is reported as hemolytic necrotic and histotoxic
(Quinn et al.
Neutrophils are essential to contain and clear infectious agents, but due to their indiscriminate histotoxic
potential they are tightly regulated by a mechanism that involves "priming" before full activation .
The reasons for such oxygen deprivation to the brain vary and include cardiac arrest, inadequate blood flow, histotoxic
causes like poisoning and trauma to brain and body as in strangulation and can occur at high altitudes in the absence of oxygen and low blood flow.
Hypoxia: This occurs when the utilization of oxygen by the body tissues is interfered with.
Clostridial toxins involved in human enteric and histotoxic
Clostridium chauvoei, the etiologic agent of blackleg, is a grampositive, motile, histotoxic
, and sporulating anaerobic bacterium (QUINN et al., 2011).