historical controls

historical controls

use of historical information as a comparison group in a study; that is a before and after comparison.
References in periodicals archive ?
Historical controls for comparable patients over sixty years of age who reach first complete remission show median OS since initial diagnosis of 9.
Early exploratory clinical results suggest that TG02 induces immune response in patients, with high activation status of tumour-infiltrating T-cells, when compared to historical controls.
Furthermore, these results suggest that the observed gains exceed the expected rates of spontaneous recovery in a closely matched population of historical controls.
Because of the retrospective nature of this study, these participants were observed at a time in the past and are labeled as historical controls.
As an indication on the basis of historical controls in 2015, the estimated number of trainees per batch is
The return rate at 1-6 months after treatment among 1,454 patients who received enhanced educational information about reinfection and the importance of retesting during the first phase of the InTOUCH study was 59%, and the return rate among 575 patients who received that educational information along with customized reminders and / or a mailed-in home testing kit in a second phase was 62%, compared with a return rate of 54% among 2,696 historical controls, Holly Howard reported at a conference on STD prevention sponsored by the Centers for Disease Control and Prevention.
Methods: The prospective study with historical controls was conducted at Cairo University Paediatric Hospital, from February to July 2012, and comprised 360 newborns with indirect hyperbilirubinaemia.
The observed incidence rate of shingles in historical controls is about 13 cases / 1,000 person-years.
We know from historical controls that the risk of relapse increases after the second relapse.
Additionally, if the historical controls are not treated, the patients will not show the benefits (e.
4 months, double the 15 months of historical controls in the published literature.

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