histoplasmin

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Related to histoplasmin: histoplasmin test

histoplasmin

[his″to-plaz´min]

a skin test antigen prepared from the fungus Histoplasma capsulatum. Because positive skin tests are common in endemic areas and indicate only previous exposure, not necessarily active disease, histoplasmin is not useful in diagnosis of histoplasmosis. It is used primarily in epidemiologic surveys and in testing for cutaneous anergy in diagnosis of immunodeficiency.

his·to·plas·min

(his'tō-plas'min),

An antigenic extract of Histoplasma capsulatum, used in immunologic tests for the diagnosis of histoplasmosis; also used in skin test surveys of populations to determine the geographic distribution of the fungus and to predict those who are endemic for histoplasmosis.

histoplasmin

/his·to·plas·min/ (-plaz´min) a skin test antigen prepared from mycelial phase Histoplasma capsulatum; used primarily in epidemiologic surveys and in testing for cutaneous anergy in diagnosis of immunodeficiency.

his·to·plas·min

(his'tō-plaz'min)

An antigenic extract of Histoplasma capsulatum, used in immunologic tests for the diagnosis of histoplasmosis; also used in skin test surveys of populations to determine the geographic distribution of the fungus and to predict those that are endemic for histoplasmosis.

his·to·plas·min

(his'tō-plaz'min)

An antigenic extract of Histoplasma capsulatum; used in immunologic tests.

histoplasmin

a preparation of growth products of Histoplasma capsulatum, injected intracutaneously as a test for histoplasmosis.

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References in periodicals archive ?

Histoplasmin and paracoccidioidin skin reactivity in infantile population of northern Argentina.

Estudio epidemiologico de la paracoccidioidomicosis e histoplasmosis en una poblacion suburbana de San Felix, estado Bolivar, Venezuela

The disease has worldwide distribution and, in some regions, up to 30% of the population show positive reaction to histoplasmin.

Histoplasmosis: the radiologic mimic and the disease spectrum--a guide for the practicing radiologist

Analysis of these data indicates that the use of more than three of the four most commonly reactive control tests (Candida, mumps, and histoplasmin or tetanus) yielded minimal additional precision in the determination of skin test anergy compared with using all five control skin tests.

Selection of skin test antigens to evaluate PPD anergy

Of 72 outbreak investigations that used the histoplasmin skin test, 71 occurred before 1990.

Epidemiology of histoplasmosis outbreaks, United States, 1938-2013

Notably, these histoplasmosis diagnoses were based on chest radiograph findings and positive results for histoplasmin skin tests, which can cross-react with Coccidioides.

Mycotic infections acquired outside areas of known endemicity, United States

2) Routine skin testing with histoplasmin in histoplasmosis-endemic areas is not predictive of disease and should not be performed (EII).

1997 USPHS/IDSA guidelines for the prevention of opportunistic infections in persons infected with human immunodeficiency virus

In southern Kentucky, middle Tennessee, and surrounding areas, histoplasmin skin testing has been positive in up to 95% of the population (3).

Histoplasmosis - Kentucky, 1995

Worldwide geographic distribution of histoplasmosis and histoplasmin sensitivity.

Geographic distribution of endemic fungal infections among older persons, United States

An atlas of sensitivity to tuberculin, PPD-B and histoplasmin in the United States.

Mycobacterium avium lymphadenopathy among children, Sweden

Skin reaction to histoplasmin in histoplasmosisendemic areas showed a 3% prevalence (10), but variety capsulatum and variety duboisii were not able to be differentiated.

Literature review and case histories of histoplasma capsulatum var. duboisii infections in HIV-infected patients

In a survey of histoplasmin skin tests conducted in Taiwan in the 1950s, only 7 (0.

Indigenous case of disseminated histoplasmosis, Taiwan

The distribution of histoplasmosis has been largely described on the basis of these outbreak reports and histoplasmin skin-test surveys (1-5).