histoplasmin


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Related to histoplasmin: histoplasmin test

histoplasmin

 [his″to-plaz´min]
a skin test antigen prepared from the fungus Histoplasma capsulatum. Because positive skin tests are common in endemic areas and indicate only previous exposure, not necessarily active disease, histoplasmin is not useful in diagnosis of histoplasmosis. It is used primarily in epidemiologic surveys and in testing for cutaneous anergy in diagnosis of immunodeficiency.

his·to·plas·min

(his'tō-plas'min),
An antigenic extract of Histoplasma capsulatum, used in immunologic tests for the diagnosis of histoplasmosis; also used in skin test surveys of populations to determine the geographic distribution of the fungus and to predict those who are endemic for histoplasmosis.

his·to·plas·min

(his'tō-plaz'min)
An antigenic extract of Histoplasma capsulatum, used in immunologic tests for the diagnosis of histoplasmosis; also used in skin test surveys of populations to determine the geographic distribution of the fungus and to predict those that are endemic for histoplasmosis.

his·to·plas·min

(his'tō-plaz'min)
An antigenic extract of Histoplasma capsulatum; used in immunologic tests.
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References in periodicals archive ?
An atlas of sensitivity to tuberculin, PPD-B, and histoplasmin in the United States.
The disease has worldwide distribution and, in some regions, up to 30% of the population show positive reaction to histoplasmin. There is a striking association between the occurrence of this disease and the nearby presence of fowl and other birds.
Analysis of these data indicates that the use of more than three of the four most commonly reactive control tests (Candida, mumps, and histoplasmin or tetanus) yielded minimal additional precision in the determination of skin test anergy compared with using all five control skin tests.
Prevalence of sensitivity to coccidioidin, with special reference to specific and nonspecific reactions to coccidioidin and to histoplasmin. Dis Chest.
(2) Routine skin testing with histoplasmin in histoplasmosis-endemic areas is not predictive of disease and should not be performed (EII).
According to histoplasmin skin test surveys performed in the 1950s and 1960s in the United States, areas surrounding the Ohio and Mississippi River Valleys are recognized as the regions of predominant histoplasmosis endemicity (5).
In southern Kentucky, middle Tennessee, and surrounding areas, histoplasmin skin testing has been positive in up to 95% of the population (3).
Paracoccidioide and histoplasmin sensitivity in Tupi-Monde Amerindian populations from Brazilian Amazonia.
In the United States, histoplasmosis-endemic areas were established during the 1940s-1950s by using nationwide skin testing to evaluate histoplasmin sensitivity among young adults (2).
Histoplasmosis-endemic areas were also established by using nationwide skin testing to evaluate histoplasmin sensitivity among [approximately equal to]70,000 white persons, 17-21 years of age, who were lifetime residents of a single county (35).
Worldwide geographic distribution of histoplasmosis and histoplasmin sensitivity.