KAT7

(redirected from histone acetyltransferase MYST2)

KAT7

A gene on chromosome 17q21.32 that encodes a component of the HBO1 complex which is responsible for the bulk of histone H4 acetylation. KAT7 specifically represses AR-mediated transcription; it may regulate DNA replication by chromatin acetylation and act as a coactivator of TP53-dependent transcription.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
(2015) The histone acetyltransferase Myst2 regulates Nanog expression, and is involved in maintaining pluripotency and self-renewal of embryonic stem cells.
Full browser ?