was diagnosed when patients presented with papular and nodular lesions, confirmed by histopathology through the predominance of spindle-shaped cells and unusually large numbers of acid-fast bacilli.
Concordance in case of indeterminate and histoid leprosy
were also included.
', first described by wade, is an unusual variant of bacilliferous leprosy with classical clinical, histopathological and bacteriological findings with 3-6% incidence.
Of the 11 cases of leprosy, 7 cases (63.63%) were of lepromatous leprosy, 2 cases each were of histoid leprosy
, and tuberculoid leprosy.
Multiple neurofibromatosis with histoid leprosy
. Int J Lepr Other Mycobact Dis.
A clinical diagnosis of HD-Indeterminate was made in 3 patients (6.7%), HD-TT in 1 patient (2.2%), HD-BT in 28 patients (62.2%), HD-BL in 5 patients (11.1%), HD-LL in 7 patients (15.6%) and Histoid leprosy
in 1 patient (2.2%).
(HL) is a rare variant of multibacillary leprosy described by Wade, (1) clinically characterised by firm, reddish, or skin-coloured, shiny, dome-shaped or oval papules and nodules on normal appearing skin.
On the basis of the clinical findings, they were subdivided into subtypes of leprosy: BL leprosy, 29.03% (n = 18); BT leprosy, 27.14% (n = 17); TT leprosy, 17.24% (n = 11); and LL, 9.46% (n = 6), of which 3 cases were of histoid leprosy
, Mid-borderline leprosy, 6.45% (n = 4), and indeterminate leprosy, 5.08% (n = 3), were also found [Figure 1].
Abstract Histoid leprosy
is one of the rare kinds of lepromatous leprosy with specific clinical pathologic manifestations.
Out of all the patients of LL, 2 patients were diagnosed having histoid leprosy
The uncommon disease presentations include localized lepromatous disease presenting with single nodule or localized area of papules and nodules, histoid leprosy
, lucio leprosy and spontaneous ulcerations seen in long-standing untreated lepromatous leprosy.
Many drugs like antitubercular, antibiotics, steroids, dapsone and vitamins have variable efficacy.2 The condition has to be differentiated from similar clinical entities like acne, lupus vulgaris, granulomatous rosacea, sarcoidosis and histoid leprosy