histocompatibility

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Related to histocompatibility: histocompatibility complex, Histocompatibility antigens, Histocompatibility testing

histocompatibility

[his″to-kom-pat″ĭ-bil´ĭ-te]

1. the quality of a cellular or tissue graft enabling it to be accepted and functional when transplanted to another organism.

2. the degree to which two individuals are histocompatible. adj., adj histocompat´ible.

his·to·com·pat·i·bil·i·ty

(his'tō-kom-pat'i-bil'i-tē),

A state of immunologic similarity (or identity) that permits successful homograft transplantation.

Farlex Partner Medical Dictionary © Farlex 2012

histocompatibility

(hĭs′tō-kəm-păt′ə-bĭl′ĭ-tē)

n. pl. histocompatibili·ties

A state or condition in which the absence of immunologic interference permits the grafting of tissue or the transfusion of blood without rejection.

his′to·com·pat′i·ble adj.

his·to·com·pat·i·bil·i·ty

(his'tō-kŏm-pat'i-bil'i-tē)

A state of immunologic similarity (or identity) that permits successful homograft transplantation.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

histocompatibility

Sufficient affinity between the genetic composition (genotypes) of donor and host to allow successful tissue or organ grafting.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

histocompatibility

the acceptance by a recipient of tissue transplanted from a donor, a state that is determined by histocompatability ANTIGENS.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Histocompatibility

The major histocompatibility determinants are the human leukocyte antigens (HLA) and characterize how well the patient and donor are matched.

Mentioned in: Bone Marrow Transplantation

his·to·com·pat·i·bil·i·ty

(his'tō-kŏm-pat'i-bil'i-tē)

State of immunologic similarity that permits successful homograft transplantation.

Medical Dictionary for the Dental Professions © Farlex 2012

References in periodicals archive ?

The influence of the swine major histocompatibility genes on antibody and cell-mediated immune responses to immunization with an aromatic-dependent mutant of Salmonella typhimurium.

Genetic association of swine leukocyte antigen class II haplotypes and body weight in Microminipigs

The antigens of the HLA system are determined by genes present in the major histocompatibility complex which is located on the short arm at the 6th chromosome (6p21.3) in humans and extends over some 4 centimorgans of DNA, about 4 x[10.sup.6] base pair.

THE HUMAN LEUKOCYTE ANTIGEN SYSTEM AND TRANSPLANTATION IMMUNOLOGY/SISTEM HUMANIH ANTIGEN LEUKOCITA ITRANSPLANTACIONA IMUNOLOGIJA

The major histocompatibility complex (MHC) encodes the cellular glycoproteins responsible for presenting self or non-self antigens to T cell receptors (TCR), and thereby initiate immune responses in invertebrates (Rothbard et al., 1991; Sommer, 2005).

MOLECULAR CHARACTERIZATION, POLYMORPHISM AND EXPRESSION ANALYSIS OF SWAMP EEL MAJOR HISTOCOMPATIBILITY COMPLEX CLASS II B GENE, AFTER INFECTION BY AEROMONAS HYDROPHILIA

This example shows the distinct connection between peptide binding profiles and immunogenicity and started a new era of histocompatibility rating.

Soluble HLA technology as a strategy to evaluate the impact of HLA mismatches

"Our results confirm the strong role of the major histocompatibility complex genes in MS, and provide a definitive statement that no other region of the genome harbors a gene with a similar overall influence on MS genetics," Dr.

Large study of multiple sclerosis points to chromosome 6

Researchers have already identified a set of genetic molecules known as the major histocompatibility complex (MHC) as the ''susceptibility locus'' for the disease.

Scientists identify gene thought to cause diabetes

In all higher species, these signature proteins are referred to as the major histocompatibility complex, or MHC.

Immunology for the rest of us

Boffins in Chicago have been studying a cute little cluster of genes they call the Major Histocompatibility Complex.

Gland of our fathers; Valley Boy

Experts tested 49 unmarried women for Major Histocompatibility Complex (MHC) by getting them to smell men's dirty T-shirts.

WOMEN ON THE SNIFF FOR DAD SUBSTITUTE

A cluster of immune response genes called the Major Histocompatibility Complex (MHC) is known to influence pheromones in animals and humans.

Fatherly odour could turn women on to potential partners; RESEARCH: Females can sniff out men with a similar genetic smell to their own, which is normally inherited from the male side of their families

Macrophages have a specialized set of molecules, called MHC-II (which stands for class II major histocompatibility complex).

How TB Evades Immune System Detection

After several medical evaluations, physicians discovered Lawrence had an immune deficiency disease called Major Histocompatibility Complex Class II deficiency.