is composed of spindle to histiocytic cells with entrapped hyaline collagen bundles at the peripheries of the lesion.
The origin of the term "malignant fibrous histiocytoma
(MFH)" dates back to the early 1960s.
Bacchini et al., "Benign fibrous histiocytoma
of bone," The Journal of Bone & Joint Surgery, vol.
Hollema et al., "Inclusion of malignant fibrous histiocytoma
in the tumour spectrum associated with hereditary non-polyposis colorectal cancer," Genes, Chromosomes and Cancer, vol.
Overall histologic and immunohistochemical staining features were those of undifferentiated pleomorphic sarcoma (pleomorphic malignant fibrous histiocytoma
The differential diagnosis is fairly broad and includes phlegmon/abscess, nerve sheath tumor, synovial sarcoma, fibrous histiocytoma
(benign, malignant and angiomatoid forms), angiosarcoma, and fibromatosis.
This tumor's differential diagnoses include adenomyoepithelioma, phyllodes tumor, adenoleiomyoma, fibroadenoma with prominent smooth muscle, fibromatosis, benign spindle cell tumor of the breast, fibrous histiocytoma
, myoid hamartoma, myoepithelioma, fibromato-sis-like low-grade metaplastic carcinoma and leiomyosarcoma of the breast (9).
Malignant fibrous histiocytoma
: an analysis of 200 cases.
The differential diagnosis of retroperitoneal schwannoma includes paraganglioma, neurofibroma, ganglioneuroma, tumors of mesodermal origin and retroperitoneal malignancies (malignant fibrous histiocytoma
, lymphoma and liposarcoma) (3).
Cytologic atypia, giant cells in the fibrohistiocytic type and an appearance of a prominent storiform pattern with an SFT may bring malignant fibrous histiocytoma
Figures 1-3 are depicting microscopic pictures of teratocarcinoma, seminoma and malignant fibrous histiocytoma
The differential diagnosis of the lacrimal gland MEC on imaging includes inflammatory myofibroblasts tumour, solitary fibrous tumour, alveolar soft part sarcoma, giant cell angiofibroma fibrous histiocytoma
, and hemangiopericytoma.