histidine decarboxylase


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his·ti·dine de·car·box·yl·ase

[MIM*142704]
an enzyme catalyzing the pyridoxal-phosphate-dependent decarboxylation of l-histidine to histamine and CO2; thus, it plays a role in constriction of bronchial smooth muscle.

his·ti·dine de·car·box·yl·ase

(his'ti-dēn dē'kahr-bok'sil-ās)
An enzyme catalyzing the decarboxylation of l-histidine to histamine and CO2; it plays a role in constriction of bronchial smooth muscle.
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References in periodicals archive ?
Promising histamine producing isolates were further screened for histidine decarboxylase (HDC) gene.
High Frequency of Histamine-Producing Bacteria in the Enological Environment and Instability of the Histidine Decarboxylase Production Phenotype.
Histamine levels in cells and tissues are regulated by histidine decarboxylase (HDC), the only enzyme that catalyzes the formation of histamine from L-histidine (25).
HDC: histidine decarboxylase, CgA: chro-mogranin A, PNECs: pulmonary neuroendocrine carcinomas, TC: typical carcinoids, AC: atypical carcinoids, SCLC: small cell lung carcinomas, LCNEC: large cell neuroendocrine carcinomas
Immunohistochemical detection of histidine decarboxylase in neoplastic mast cells in patients with systemic mastocytosis.