The antiemetics market is segmented by type of drugs into different categories such as 5-HT3 receptor antagonists, Dopamine antagonists, NK1 receptor antagonist, Antihistamines (H1 histamine receptor antagonists
), Cannabinoids, Benzodiazepines, Anticholinergics, Steroids and Others.
Synergy Pharmaceuticals announced that the company will present new analyses that further reinforce the efficacy and safety of TRULANCE for adult patients with chronic idiopathic constipation or irritable bowel syndrome with constipation, specifically in patients aged 65 and older and in patients using concomitant acid suppression medications such as proton pump inhibitors and/or histamine receptor antagonists
. These findings will be presented via two poster presentations this week at the American College of Gastroenterology Annual Scientific Meeting in Philadelphia.
In the early clays, clinicians seemed in-dined to start patients on the histamine receptor antagonists
as first-line therapy, reserving PPIs for more recalcitrant cases.
Histamine receptor antagonists are available over the counter in half the strength of their prescription doses.
PPIs control symptoms and heal esophagitis in more patients than do histamine receptor antagonists. They also work faster; most people experience relief in days or a few weeks, compared with a month or more with the histamine receptor antagonists.