hippuric acid


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hippuric acid

 [hĭ-pu´rik]
a compound formed by conjugation of benzoic acid and glycine; it occurs in the urine of herbivorous animals, rarely in human urine.

hip·pu·ric ac·id

(hi-pyūr'ik as'id),
A detoxification and excretory product of benzoate found in the urine of humans and many herbivorous animals; used therapeutically in the form of its salts (hippurates of calcium and ammonium).
[G. hippos, horse, + ouron, urine]

hippuric acid

/hip·pu·ric ac·id/ (hĭ-pūr´ik) C6H5·CO·NH·CH2·COOH, formed by conjugation of benzoic acid and glycine.

hippuric acid

Etymology: Gk, hippos, horse, ouron, urine; L, acidus, sour
a detoxication product in the urine of some animals, used as a medication in the treatment of arthritic diseases.

hip·pu·ric ac·id

(HA) (hi-pyūr'ik as'id)
A detoxification and excretory product of benzoate found in the urine of humans and many herbivorous animals. A derivative, paraaminohippuric acid, is used in renal testing.
[G. hippos, horse, + ouron, urine]

hippuric acid

a compound formed by conjugation of benzoic acid and glycine; it occurs in the urine of herbivorous animals, rarely in human urine.

hippuric acid acid test
has been tested as a means of assessing hepatic efficiency but is not favored.
References in periodicals archive ?
Urine samples were obtained at the beginning and end of an 8-hr work shift and used to measure hippuric acid levels.
We measured urinary hippuric acid according to the recommendations of the National Institute for Occupational Safety and Health (NIOSH 1994).
In all cases, the concentrations of toluene, gasoline, acetone, ethylacetate, and methylenediphenyl diisocyanate (MDI) in workplace air and the concentration of hippuric acid (HA) in the urine were determined.
Urinary hippuric acid and blood hemoglobin levels in exposed shoe workers and control subjects (means [+ or -] SD).
Synthesis of hippuric acid with inverse phase transfer catalyst in a heterogeneous liquid-liquid reaction system.
Among these were hippuric acid, homovanillic acid, uracil, 5-fluorouracil, and tryptophan.
Urine from healthy infants contained dominant peaks of uric acid (UA), urea, creatinine, and hippuric acid and usually various amounts of hypoxanthine (HX), xanthine (X), 7-methylguanine, pseudouridine, and uridine.
After the addition of 10 [micro]L of internal standard (o-methylhippuric acid), hippuric acid and o-methylhippuric acid were extracted from the acidified solution into 300 [micro]L of ethyl acetate by vortex-mixing for 30 s.
In the 1990s, however, the monohydrate form was still considered "unusual" or was likely to be misidentified as hippuric acid crystals in cases of ethylene glycol poisoning [29].
Although the extraction recoveries of lactic acid, hippuric acid, and citric acid were only 39%, 26%, and 10%, respectively, they could be sufficiently detected in biological samples.