hippuric acid


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hippuric acid

 [hĭ-pu´rik]
a compound formed by conjugation of benzoic acid and glycine; it occurs in the urine of herbivorous animals, rarely in human urine.

hip·pu·ric ac·id

(hi-pyūr'ik as'id),
A detoxification and excretory product of benzoate found in the urine of humans and many herbivorous animals; used therapeutically in the form of its salts (hippurates of calcium and ammonium).
[G. hippos, horse, + ouron, urine]

hip·pu·ric ac·id

(HA) (hi-pyūr'ik as'id)
A detoxification and excretory product of benzoate found in the urine of humans and many herbivorous animals. A derivative, paraaminohippuric acid, is used in renal testing.
[G. hippos, horse, + ouron, urine]
References in periodicals archive ?
Horinouchi, "Method development and validation for simultaneous quantitation of endogenous hippuric acid and phenylacetylglycine in rat urine using liquid chromatography coupled with electrospray ionization tandem mass spectrometry," Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol.
Hippuric acid and indoleacetic acid were purchased from Tokyo chemical industry (Tokyo, Japan).
It is based on the fact that hippuric acid has no known function other than to facilitate excretion of benzoid-type of compounds.
Use of para-amino hippuric acid to measure blood flows through portal-drained-viscera, liver and hindquarters in sheep.
The further analysis of cranberry metabolites showed that the urine from Group III participants contained significantly higher levels of hippuric acid, conjugates of some other phenolic acids and quercetin glucuronide, but otherwise showed no significant increase in acidity.
[6.] Zhao H., Zhang Y,, Yuan Z.: "Determination of Dopamine in the Presence of Ascorbic Acid Using Poly (hippuric acid) Modified Glassy Carbon Electrode".
Results Hippuric acid concentration was found to be within normal values; by contrast, phenol and methylhippuric acid sample concentrations were above normal values by 3,3 % and 50,8 %, respectively.
Routine laboratory monitoring revealed increased concentrations of urinary 2.5 hexandione (n-hexane metabolite) and hippuric acid (toluene metabolite) in the period immediately preceding the visual loss.
After oral uptake, Na-benzoate is rapidly absorbed from the gastro-intestinal tract and combines with glycine in the liver forming hippuric acid (Feldman et al., 1970; US FDA 1972; WHO 1996; Feillet et al., 1998) which is rapidly excreted via the urine (about 75%) within 6hr and rest within 2-3 days (Kubota et al., 1988; Fujii et al., 1991; Kubota et al., 1991).
Cranberries can help ward off bladder infections such as cystitis, because the hippuric acid that they contain has the power to repel E-coli bacteria, which can settle in the urinary tract.