The increased cortisol levels detected in the test of children and adolescents with PTSD indirectly suggest a possible mechanism for changes of hippocampal formation.
Studies on the changes in hippocampal formation of children and adolescents with PTSD are still very limited.
In monkey, increased ipsilateral linkage was shown between hippocampal formation as well as the subiculum and neocortex in evolutionary development, which indicates the development of hemispheric specialization (31).
Asymmetry of neuron numbers in the hippocampal formation of prenatally malnourished and normally nourished rats: A stereological investigation.
In conclusion, there is a growing body of evidence to suggest that the hippocampal formation in humans contributes to the encoding and retrieval of spatial (topographical) information.
Thus, the majority of recent theories of hippocampal function have at their core the organizing principle that representations of objects/ events and their spatiotemporal context are integrated together (or indeed separated) from each other in a neural network instantiated in the hippocampal formation.
The act of consciously retrieving a word from memory may stimulate the hippocampal formation much more than simply recognizing a previously studied word, they add.
However, other studies have found relatively weak responses of the hippocampal formation on memory tests similar to Schacter's high recall, explicit condition, according to Steven E.
Up to this point in this follow-up investigation, we had found that monkeys with ablation of the
hippocampal formation were initially impaired, and later recovered, the ability to learn a spatial discrimination on the basis of egocentric cues (spatial reversal, delayed alternation).
The most complete magnetic resonance images of the
hippocampal formation are obtained when patients lie down with their heads tilted back, a procedure not used previously, say Gary A.
1989) Configural association theory: The role of the
hippocampal formation in learning, memory, and amnesia.
At our institution, in addition to routine brain imaging (sagittal T1WI, axial T1WI, intermediate and T2WI), we also use high-resolution coronal T2-weighted fast spin echo (FSE) imaging to optimally define the
hippocampal formations.
