lymphadenopathy

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Related to hilar lymphadenopathy: hilar lymph nodes

lymphadenopathy

 [lim-fad″ĕ-nop´ah-the]
disease of the lymph nodes; called also adenopathy.
angioimmunoblastic lymphadenopathy (angioimmunoblastic lymphadenopathy with dysproteinemia (AILD)) a systemic disorder resembling lymphoma characterized by fever, night sweats, weight loss, generalized lymphadenopathy, hepatosplenomegaly, macropapular rash, polyclonal hypergammaglobulinemia, and Coombs'-positive hemolytic anemia. It is considered to be a nonmalignant hyperimmune reaction to chronic antigenic stimulation; there is proliferation of B cells accompanied by profound deficiency of T cells. The disease follows a progressive but extremely variable course: some patients survive for a long period without chemotherapy; in other patients, overwhelming infections rapidly lead to death
dermatopathic lymphadenopathy regional lymph node enlargement associated with melanoderma and other dermatoses marked by chronic erythroderma.
immunoblastic lymphadenopathy angioimmunoblastic lymphadenopathy.
lymphadenopathy syndrome a condition occurring in immunocompromised individuals, characterized by unexplained lymphadenopathy for 3 or more months that involves extrainguinal sites, which on biopsy reveal nonspecific lymphoid hyperplasia. See also AIDS-related complex.

lym·phad·e·nop·a·thy

(lim-fad'ĕ-nop'ă-thē),
1. Any disease process affecting a lymph node or lymph nodes.
2. The appearance of enlarged lymph nodes found on a radiologic examination of any kind.
[lymphadeno- + G. pathos, suffering]

lymphadenopathy

(lĭm-făd′n-ŏp′ə-thē, lĭm′fə-dn-)
n. pl. lymphadenopa·thies
An enlargement of the lymph nodes, usually associated with disease.

lymphadenopathy

A generic term for lymph node enlargement of any aetiology, benign or malignant.

Lymphadenopathy, aetiology
Infection
• Viral—Infectious mononucleosis, CMV, HIV.
• Bacterial—Typhoid, TB, syphilis, Yersinia.
Malignancy
• Lymphoproliferative—especially lymphoma
• Metastases.

Storage
Lipid storage, Niemann-Pick, sphingomyelia.

Drugs
Phenytoin, allopurinol, isoniazid.

Immune
Automimmune, rheumatoid arthritis, sarcoid, GVHD.

Benign hyperplasia, Langerhans cell histiocytosis.

lymphadenopathy

Enlarged lymph nodes, follicular hypertrophy, swollen lymph glands Hematology Enlargement of lymph nodes of any etiology; the differential diagnostic considerations are multiple and divided into reactive patterns; benign lymphadenopathy is characterized by
1. Variability of the follicle–germinal center size;.
2. Lack of capsular or fat invasion;.
3. Mitotic activity confined to the germinal center;.
4. Cortical localization and inhomogeneous distribution of the follicles. See Angiography lymphadenopathy, Benign lymphadenopathy, Dermatopathic lymphadenopathy, Phenytoin lymphadenopathy, Shotty lymphadenopathy.

lym·phad·e·nop·a·thy

(lim-fad'ĕ-nop'ă-thē)
Any disease process affecting a lymph node or lymph nodes.
[G. lympha spring water +aden gland + G. pathos, suffering]

lymphadenopathy

(lim″fad″ĕ-nop′ă-thē) [ lymph- + adenopathy]
Enlarge picture
CERVICAL LYMPHADENOPATHY: Squamous cell carcinoma of the neck
Enlargement of lymph nodes (LN), typically to greater than 1.5 cm. The increased size is caused by activation and proliferation of lymphocytes and phagocytic white blood cells within the node or by invasion of the node by tumor. Most often, lymphadenopathy is found in nodes involved in local, regional, or systemic infections; it results occasionally from cancers. Lymphadenopathy may also be found in an array of other, less common illnesses, including thyroiditis, thyrotoxicosis, autoimmune diseases (e.g., rheumatoid arthritis), sarcoidosis, and drug reactions (e.g., phenytoin). See: illustration

Enlarged LNs may be tender or not; tenderness often is present when lymph nodes swell rapidly (e.g., in response to infections, hypersensitivity reactions, or some fulminant lymphomas). Rock-hard, enlarged, and immobile LNs are typical of metastatic cancer, whereas rubbery LNs are found in lymphomas. LNs that do not resolve spontaneously within 4 to 6 weeks, or for which no obvious explanation exists, usually are sampled by biopsy or aspiration.

dermatopathic lymphadenopathy

Widespread lymphadenopathy secondary to various skin disorders.
See: table
CategoryExamplesLocationAge of patientTextureSizeAssociated signs or symptomsDiagnostic testsNecessity for biopsy or aspirate
Bacterial infectionStrep throat; cat scratch diseaseAngle of the jaw; axilla, neckChild or preteen; anyRelatively soft and tender; relatively soft and tender1 sq. cm; > 1 cmFever, sore throat, tonsillar exudate, malaise, headache, difficulty swallowing; may have fever, night sweats, weight lossCan be diagnosed clinically; antibody blood testsNo; not usually
GranulomaTuberculosis; sarcoidosisNeck, chest; hilum of the lung and other locationsAny; usually adultsRelatively soft and tender; rubbery> 1 cm; > 1 cm, sometimes massiveMay have fever, night sweats, weight loss, productive sputum; cough, shortness of breath, may have systemic illness, or be asymptomaticTuberculin (purified protein derivative), interferon blood test, sputum for acid-fast bacilli; blood for ACE levelsOccasionally; often
Metastatic cancerBreast cancerAxilla next to the breastAdultsStoneEspecially likely if > 2 cmLump in the breastMammography, ultrasound, other imaging techniquesYes
LymphomaHodgkin lymphomaChest, neck, axilla, groin, or all of these Young adultRubbery> 1 cmMay have fever, night sweats, weight loss, enlarged spleenRadiologic imagingYes
Viral infectionMononucleosis; HIV/AIDSHead and neck, spleen; generalizedYoung adult; any, but most often young adult or adultRubbery; firmAbout 1 cm; variableMay have fever, night sweats, weight loss; fever, night sweats, weight loss, or symptoms of opportunistic infectionTests for Epstein-Barr virus, heterophile antibody; antibody blood testsNo; not usually

lymphadenopathy

Any disease process affecting a LYMPH NODE. Also known as lymphadenosis.

lymphadenopathy

An enlargement of a lymph gland. The preauricular lymph node located 1 cm in front of the external ear drains the orbital region and is sometimes involved with eyelid and conjunctival infection (e.g. adult inclusion conjunctivitis, follicular conjunctivitis). Syn. adenopathy (although strictly speaking this term refers to the enlargement of any gland).

lym·phad·e·nop·a·thy

(lim-fad'ĕ-nop'ă-thē)
1. Any disease process affecting lymph nodes.
2. The appearance of enlarged lymph nodes found on x-rays.
[G. lympha spring water + aden gland + G. pathos, suffering]

Patient discussion about lymphadenopathy

Q. my friend ate a bar of chocolate and now her left neck gland is swollen any ideas why? no other symptoms

A. it can be an infection -just like brandon said- or although this is rare, it can also be an allergic reaction.
if it is an infection, you can usually find such other infection symptoms like : fever, pain in that swollen area, increased white blood cells (in blood work test), etc.

if it is an allergy, usually it will fade away itself in couple of days, or you can just try to consume anti-allergic drugs, such as : loratadine and maybe combined with dexamethasone.

Good luck, and stay healthy always..

More discussions about lymphadenopathy
References in periodicals archive ?
Ocular No ocular involvement involvement (n = 39) (n =16) Mean age 57.1 [+ or -] 15.5 48.0 [+ or -] 13.7 Female/male ratio 35/4 10/6 BHL (a) in radiography 34 (87.2%) 15 (93.8%) Increased ACE (b) 29 (74.4%) 8 (50.0%) ACE (b) level 77.1 [+ or -] 40.9 61.7 [+ or -] 33.9 Visual acuity at 0.83 [+ or -] 0.19 0.90 [+ or -] 0.14 last visit Systemic treatment 28 (71.8%) 5 (31.3%) Immunosuppression 14 (35.9%) 0 (0.0%) P value Mean age 0.045 Female/male ratio 0.048 BHL (a) in radiography 0.66 Increased ACE (b) 0.12 ACE (b) level 0.19 Visual acuity at 0.15 last visit Systemic treatment 0.007 Immunosuppression 0.005 (a) Bilateral hilar lymphadenopathy; (b) angiotensin-converting enzyme.
In present study, bilateral hilar lymphadenopathy plus pulmonary opacity was the most common radiological presentation of sarcoidosis.
In most cases (except for the classic presentation of arthritis, erythema nodosum, and bilateral hilar lymphadenopathy known as Lofgren's syndrome), biopsy of the affected organ should be obtained.
Tularemia used as an air-born biological weapon would likely result in symptoms 3-5 days after the agent is inoculated into the community and present as a rapid outbreak of undifferentiated febrile illness with incipient pneumonia, pleuritis, and hilar lymphadenopathy (Dennis et.
Pleural thickening with a nodular mass within lung parenchyma and prominent hilar lymphadenopathy favors a diagnosis of adenocarcinoma with pleural involvement.
He was admitted to a hospital after a chest radiograph indicated bilateral lower lobe infiltrates with extensive mediastinal and hilar lymphadenopathy. He was presumed to have bacterial pneumonia and was treated with antibiotics.
Chest imaging and fluorodeoxyglucose-positron emission tomography found nonspecific pulmonary nodules and hilar lymphadenopathy. Additional unremarkable studies included bone marrow biopsies, lung biopsies, and sinus biopsies.
Sarcoidosis is a multisystem disease of unknown etiology defined by noncaseating granulomas that may be seen on lung imaging as bilateral hilar lymphadenopathy and/or interstitial lung disease (ILD) [1, 2].
CT Chest shows lung mass in case of primary pulmonary lymphoma and pleural, mediastinal and hilar lymphadenopathy in case of secondary pulmonary lymphoma (Ref.
The CT scan confirmed the stability of the pulmonary nodules with no changes to heart size and no evidence of mediastinal or hilar lymphadenopathy.
X-ray chest (PA) view showed bilateral hilar lymphadenopathy (fig-2).