In the wild, ongoing chromosomal rearrangements lead to considerable changes in the numbers, sizes, and positions of highly repetitive DNA
clusters and underlie the divergence of natural populations .
The variability in DNA amount has often been attributed to loss or addition of highly repetitive DNA
sequences rather than to the AT- or GC-rich sequences in the genome (Martel et al.
To analyze the stability of Norstar BAC clones, 10 clones of which seven carried highly repetitive DNA
An Austrian biologist theorized that the erosion of telomeres, highly repetitive DNA
at the end of chromosomes, might function as a kind of internal clock that determines when a species will become extinct.
Localized highly repetitive DNA
sequences in vertebrate and invertebrate genomes, pp.
This requires cloning highly repetitive DNA
, which tends to be unstable," says Cappello, who conducted his postdoctoral training at the Whitehead Institute for Biomedical Research at Massachusetts Institute of Technology, Cambridge.