high-throughput screening


Also found in: Dictionary, Thesaurus, Financial, Acronyms, Encyclopedia, Wikipedia.

high-throughput screening

The testing of the biological or pharmacological properties of molecules by immersion in a large number of chemical baths or cellular systems. It is used, e.g., to determine whether any of a group of chemicals has specific therapeutic actions.
See also: screening
Mentioned in ?
References in periodicals archive ?
"The significant trends in high-throughput screening include more cell-based assays, chemiluminescence and fluorescence, which replace radioactivity, homogeneous assay formats, multiplexing and smaller assay volumes in higher density plates," according to Jon P.
Invenra has developed its own pipeline of bispecifics and has several strategic alliances in which antibody drug developers use Invenra's high-throughput screening technologies to identify molecules with biological relevance.
High-throughput experimentation applies the techniques of high-throughput screening, first developed for the pharmaceutical industry, to applications in the chemical and energy industries.
Founded in 2002, MerLion Pharmaceuticals is a research-oriented pharmaceutical company that has advanced fermentation technology and high-throughput screening technology.
Work toward improving the NTP's use of high-throughput screening will include cataloguing approaches being used in the public domain and applying these assays to more than 500 agents that have already gone through the full two-year bioassay that is the NTP's current gold standard.
"Pharmacopeia is very pleased to have the opportunity to apply our expertise in lead discovery, our unique compound collection and our high-throughput screening capabilities to helping a successful biotechnology company like Neurocrine discover the lead compounds which will be their next generation of clinical candidates," noted Dr.
(Santa Clara, Calif.) has led to the disco very of a new class of single-site catalysts for olefin polymerization by means of a high-throughput screening methodology, the companies announce.
Mass producing samples of films composed of two or more compounds opens the way to high-throughput screening that can narrow the hunt for new materials.
Bristol-Myers Squibb Company (NYSE: BMY) has purchased seven 3-Dimensional ThermoFluor high-throughput screening workstations.
The high-throughput screening facility, expected to open next year, will initially employ about three dozen scientists.