high-osmolality contrast medium

Imaging An ionic compound–eg, diatrizoate, iothalamate which is used as intravascular radiographic contrast media; HOCMs have up to 7 times the osmolality of plasma. See Diatrizoate, Iothalamate. Cf Low-osmolality contrast media.

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The latter finding may not apply to high-osmolality contrast medium, since all but one study included in the meta-analysis used iso- and/or low-osmolality contrast media.

Contrast-induced acute kidney injury: definition, epidemiology, and outcome

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