high-grade lymphoma

high-grade lymphoma

Oncology An aggressive lymphoma that responds poorly to chemotherapy and comprises 20% of lymphomas  Prognosis HGLs have a mean survival of < 1 yr without therapy. See Lymphoma.
References in periodicals archive ?
Since FL can transform to high-grade lymphoma, therefore patients with lymph node biopsy proven transformation were taken into account.
Diagnosis of DLBCL, Burkitt's lymphoma, plasmablastic lymphoma and high-grade lymphoma were confirmed independently on review by two authors (DA and JCM) using morphologic and immunohistochemical criteria defined in the WHO classification.
Transformation to a high-grade lymphoma occurs in 25 to 35% of patients.
Both patients presented with a morphologically high-grade lymphoma whose immuno phenotype ([CD30.
4) Intermediate and high-grade lymphoma classification is a risk factor for CNS involvement in NHL.
Transformation of lymphoplasmacytic lymphoma to high-grade lymphoma usually portends an adverse prognosis, and there is no established treatment regimen.