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Any complex of fats with protein. A conjugated protein consisting of a simple protein combined with a fat (lipid) group. The blood lipoproteins, which are the cholesterol carriers of the body, are classified by density, in accordance with the proportions of protein, as very low density (VLDL), low density (LDL) and high density (HDL). LDLs contain relatively large amounts of cholesterol. HDLs contain 50% of protein and only 20% of cholesterol. LDLs transport lipids to muscles and to fat stores and are associated with the arterial disease ATHEROSCLEROSIS and thus heart disease and STROKE. HDLs are protective against these diseases because their main role is to transport cholesterol from the periphery back to the liver. They also carry paraoxanase enzymes that limit oxidative modification of LDLs necessary before cholesterol can be laid down in arterial walls. Blood concentration of HDL cholesterol shows a strong inverse correlation with the risk of coronary heart disease.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


The packages in which cholesterol and triglycerides travel throughout the body.
Mentioned in: Lipoproteins Test
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

Patient discussion about lipoproteins

Q. what are the sources for high density lipoprotein? I have heard that high density lipoprotein is good for heart. What differences does it make in heart’s health and what are the sources for high density lipoprotein?

A. Hi Liam, it is very important that we have high density lipoprotein (HDL) in our body. The fact is that the HDL is formed inside the body. They are known as good cholesterol as they are famous for their protection for heart against the heart diseases. It has been found that Vitamin B3 or Niacin consumption increases the count of HDL. It’s good to cut on the diet having more of saturated fats and oils, which increases the chances of heart attack.

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References in periodicals archive ?
KEYWORDS: Diabetes Mellitus, Diabetic Nephropathy, Monocyte count to high-density lipoprotein cholesterol ratio.
High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules.
These included elevated triglycerides levels, decreased high-density lipoproteins, high blood pressure, and excessive blood-sugar concentrations.
Concentrations of total cholesterol, high-density lipoprotein (HDL), non-HDL cholesterol, and low-density lipoprotein (LDL) cholesterol, as well as LDL/HDL and TG/HDL ratios, were divided according to distribution quartiles.
Fielding (cardiovascular physiology, University of California-San Francisco) offers a detailed overview of the biological role of high-density lipoproteins (HDLs), summarizing current knowledge on HDL turnover, regulation, and physiology.
Reverse cholesterol transport (RCT) is the process by which high-density lipoproteins (HDL) are able to extract excess cholesterol from blood vessel walls and deliver it back to the liver and gastrointestinal tract for disposal (Figure).
It is characterized by a severe deficiency or absence of high-density lipoproteins in plasma.
High-density lipoproteins, or HDLs, appear to remove cholesterol from the vascular system.
A key factor in reaching that ripe old age appears to be maintaining good lipid profiles, especially high levels of high-density lipoproteins or HDLs.
According to researchers individuals with very low high-density lipoproteins (HDL) cholesterol had a 75 per cent higher risk of infectious disease, whereas the risk was 43 per cent higher in those with very high HDL cholesterol, reported private news channel.
High-density lipoproteins; structure, metabolism, function, and therapeutics.

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