Those men and women had previously experienced high-altitude pulmonary edema
, a potentially life-threatening condition in which fuid collects in the lungs.
Specifically, HAI includes acute mountain sickness (AMS), high-altitude cerebral edema (HACE), and high-altitude pulmonary edema
(HAPE) (Table 1).
In addition, acetazolamide (Diamox)--used empirically for more than 3 decades to prevent high-altitude pulmonary edema
(HAPE) in individuals with a history of HAPE--is, as a result of recent studies, "finally getting the respect it deserves" as an evidence-based prophylactic agent, said Dr.
Positive association of the endothelial nitric oxide synthase gene polymorphisms with high-altitude pulmonary edema
It had been assumed that avalanches and falling ice - particularly in the Khumbu Icefall on the Nepal route - were the leading causes of death and that high-altitude pulmonary edema
would be a common problem at such extreme altitude.
3) However, even while maintaining sufficient oxygen saturation, Gabry and colleagues reported patients with high-altitude pulmonary edema
arising at elevations between 4,600 and 8,000 ft.
When fluids accumulate in the lungs, High-Altitude Pulmonary Edema
(HAPE) can, in effect, drown a person.