high endothelial venule


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high endothelial venule

,

HEV

A postcapillary venule found in gut-associated lymphoid tissue, e.g., Peyer's patches, and in lymph nodes. It regulates the movement of lymphocytes in and out of the blood.
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References in periodicals archive ?
2013) Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2.
mature, non-activated) lymphocytes migrate from the peripheral blood into lymph nodes and Peyer's patches by selectively interacting with the specialized endothelium of postcapillary venules called high endothelial venules (HEVs).
2004) Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling.
2011) Novel regulators of lymphocyte trafficking across high endothelial venules.
2013) Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis.

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