high endothelial venule


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high endothelial venule

,

HEV

A postcapillary venule found in gut-associated lymphoid tissue, e.g., Peyer's patches, and in lymph nodes. It regulates the movement of lymphocytes in and out of the blood.
References in periodicals archive ?
Under physiological conditions, naive (i.e., mature, non-activated) lymphocytes migrate from the peripheral blood into lymph nodes and Peyer's patches by selectively interacting with the specialized endothelium of postcapillary venules called high endothelial venules (HEVs).
(2004) Lymphocyte trafficking across high endothelial venules: dogmas and enigmas.
(2011) Novel regulators of lymphocyte trafficking across high endothelial venules. Crit.
The lymphoma cell population was clearly composed of follicular helper T-cells and of an important FDC component, but of few high endothelial venules and EBV+, CD20+ immunoblasts.
Note the negative staining related to the high endothelial venules (Immunohistochemistry with DAB x320).
Hontsu et al., "CCR7 mediates the migration of Foxp3+ regulatory T cells to the paracortical areas of peripheral lymph nodes through high endothelial venules," Journal of Leukocyte Biology, vol.
(I) Circulating naive T (Th0) cells and regulatory T cells (Tregs) migrate to the parenchyma of draining lymph nodes via specialized postcapillary venules called high endothelial venules (HEVs).
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