high altitude cerebral edema


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A syndrome caused by rapid ascent of unacclimatised persons above 2000-2500 meters, which is attributed to vasogenic cerebral edema
Prevention Nifedipine, slow ascent to heights
Management Transport patient to a lower altitude

high al·ti·tude ce·re·bral e·de·ma

(hī al'ti-tūd ser'ĕ-brăl ĕ-dē'mă)
Brain swelling related to a fast ascent. Signs and symptoms may include fatigue, nausea, vomiting, ataxia, and altered mentation.
References in periodicals archive ?
High altitude cerebral edema (HACE) is an advanced and potentially fatal form of mountain sickness.
Severe consequences include high altitude pulmonary edema and high altitude cerebral edema, which are both medical emergencies.
Consensus Statement of the UIAA Medical Commission Vol: 2; Emergency Field Management of Acute Mountain Sickness, High Altitude Pulmonary Edema, and High Altitude Cerebral Edema; Intended for Doctors, Interested Non-medical Persons and Trekking or Expedition Operators.
Exposure to hypobaric hypoxia can result in extreme conditions, such as acute mountain sickness (AMS), high altitude pulmonary edema (HAPE), and high altitude cerebral edema (HACE), as well as other conditions, such as headache, nausea, vomiting, and gastrointestinal alterations [1-5].
52% patients had Acute Mountain Sickness, 12% hypertension, 10% High altitude cerebral edema, 8% Tension type headaches, 6% Dural venous sinus thrombosis, 6% migraine, 2% encephalitis, 2% were of Subarachnoid hemorrhage and 2% patients Hydrocephalus.
Altitude related illnesses like acute mountain sickness (AMS), high altitude pulmonary edema (HAPE) and high altitude cerebral edema (HACE) are possibly related to hypoxia induced free radical formation that alter blood-brain barrier permeability [2].

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