hexosaminidase A

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hex·os·a·min·i·dase A

a hydrolytic enzyme that acts on ganglioside GM2, producing N-acetyl-d-galactosamine and ganglioside GM3; a deficiency of this enzyme is associated with Tay-Sachs disease.
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References in periodicals archive ?
[G.sub.M2] gangliosidosis B1 variant: biochemical and molecular characterization of hexosaminidase A. Biochem Mol Med 1995;54:126-32.