hexokinase


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hexokinase

 [hek″so-ki´nās]
an enzyme that catalyzes the transfer of a high-energy phosphate group of a donor to d-glucose, producing d-glucose-6-phosphate.

hex·o·ki·nase

(heks'ō-kī'nās),
A phosphotransferase present in yeast, muscle, brain, and other tissues that catalyzes the ATP-dependent phosphorylation of d-glucose and other hexoses to form d-glucose 6-phosphate (or other hexose 6-phosphates); the first step in glycolysis; a deficiency of hexokinase can result in hemolytic anemia and impaired glycolysis.

hexokinase

/hexo·ki·nase/ (hek″so-ki´nās) an enzyme that catalyzes the transfer of a high-energy phosphate group to a hexose, the initial step in the cellular utilization of free hexoses. The enzyme occurs in all tissues as various isozymes with varying specificities; the liver isozyme (type IV) is specific for glucose and is often called glucokinase.

hexokinase

[hek′səkī′nās]
Etymology: Gk, hex, six, glykys, sweet, kinein, to move, ase, enzyme
a transferase enzyme present in all tissue that catalyzes the transfer of a phosphate group from adenosine triphosphate to glucose 6-phosphate. It is also found in yeast.

hex·o·ki·nase

(heks'ō-kī'nās)
A phosphotransferase present in yeast, muscle, brain, and other tissues that catalyzes the phosphorylation of d-glucose and other hexoses to form d-glucose 6-phosphate (or other hexose 6-phosphate) (phosphate is transferred from ATP, which is converted to ADP); the first step in glycolysis; a deficiency of hexokinase can result in hemolytic anemia and impaired glycolysis.

hexokinase

an enzyme that catalyzes the transfer of a high-energy phosphate group of ATP to a hexose sugar, usually d-glucose, producing d-glucose-6-phosphate.
References in periodicals archive ?
The actinide dependent hexokinase activity and actinide dependent ATP synthase activity were high but the blood ATP levels were low.
Like glucose, the 2-DG is taken up by cells via GLUTs and phosphorylated by hexokinase.
Membrane potential-dependent conformational changes in mitochondrially bound hexokinase of brain.
Increased Hexokinase Activity, of Either Ectopic or Endogenous Origin, Protects Renal Epithelial Cells against Acute Oxidant-induced Cell Death.
The expression of hexokinase II in clear-cell RCC is elevated.
Convergent evolution of similar enzymatic function on different protein folds: The hexokinase, ribokinase, and galactokinase families of sugar kinases.
It has been suggested that in tumours an increased ratio of hexokinase to glucose-6-phosphatase results in gradual accumulation of FDG and therefore in a further increase in SUV on delayed imaging.
226 was the one which correlated best with the hexokinase plasma reference method.
Activities of glucose and glycogen metabolizing enzymes: The activities of hexokinase and glucose6-phosphatase were determined by the methods described elsewhere (14), pyruvate kinase (15), glycogen phosphorylase (16), and fructosel, 6-bisphosphatase (17).
1) Physiologically, hemolysis can occur in several disease states such as glucose-6-phosphate dehydrogenase or hexokinase deficiency.