hexamethonium


Also found in: Dictionary, Encyclopedia, Wikipedia.

hexamethonium

(hĕks″ă-mĕ-thō′nē-ŭm)
A compound that acts as a ganglionic blocking agent, used to treat hypertension.

hexamethonium (heksəmethō-nēəm),

n a cholinergic blocking agent used to control bleeding and used in the treatment of peptic ulcers and hypertension. It produces ganglion blocking by occupying receptor sites.

hexamethonium

a ganglion-blocking quaternary ammonium compound.
References in periodicals archive ?
Similarly, if the application of saponin was preceded by the administration of hexamethonium, the strength of the contraction of stomach fundus strips induced by [alpha]-hederin was not modified.
Acetylcholine chloride, atropine sulfate, dimethylsulfondioxide (DMSO), hexamethonium bromide, isoproterenol hemisulfate, nicotine, (Sigma Chemicals Co, St.
Experiments designed to study the effect of hexamethonium (1 [micro]M) on [alpha]-hederin-induced contraction, started with a 1 h equilibration.
The administration of hexamethonium (1 [micro]M) to the incubation chamber significantly inhibited the reaction of isolated stomach fundus strips to nicotine (1000 [micro]M) (Fig.
There's a lot at stake: whether one is an aspiring Watson or Crick at a university without a first-rate library, a doctor in a meningitis laboratory in Zimbabwe, or even just a participant in a Johns Hopkins study on hexamethonium.
The first response was accompanied by a rise in systemic blood pressure, which was reduced by hexamethonium, not entirely eliminated by phentolamine but eliminated with spinal destruction to the sacral cord level.
China) Hexamethonium (BDH), Nifedipine (Alison's Drug Company), Tolazoline (Sigma) Propanol (Sigma).
Hexamethonium, a ganglion blocker, promethazine and chlorpheniramine, both of which are [H.
However, the contractile effects of ACPF, and MCAF were mediated by stimulation of muscarinic, nicotinic receptors and activation Ca channel, since atropine, hexamethonium and nifedipine were able to antagonize the effects appreciably.
injection of the ganglion blocker, hexamethonium (30 mg/kg body wt.
Hexamethonium bromide and acetylcholine chloride were purchased from Sigma Chemical Co.
Furthermore, the observed increases in both maximal percent and absolute decreases in MAP, in response to hexamethonium bromide after DOCA-salt treatment, further support the increased basal sympathetic activity in this model of hypertension.