hexamethonium


Also found in: Dictionary, Encyclopedia, Wikipedia.

hexamethonium

(hĕks″ă-mĕ-thō′nē-ŭm)
A compound that acts as a ganglionic blocking agent, used to treat hypertension.

hexamethonium

a ganglion-blocking quaternary ammonium compound.
References in periodicals archive ?
Acetylcholine chloride, atropine sulfate, dimethylsulfondioxide (DMSO), hexamethonium bromide, isoproterenol hemisulfate, nicotine, (Sigma Chemicals Co, St.
Experiments designed to study the effect of hexamethonium (1 [micro]M) on [alpha]-hederin-induced contraction, started with a 1 h equilibration.
The administration of hexamethonium (1 [micro]M) to the incubation chamber significantly inhibited the reaction of isolated stomach fundus strips to nicotine (1000 [micro]M) (Fig.
Moreover, this effect was blocked by the nicotinic antagonist hexamethonium.
isoproterenol hydrochloride (Sigma), propranolol hydrochloride (Sigma), atropine (Sigma) and hexamethonium chloride (K & K Laboratories, Inc.
When hexamethonium was given, the hypotensive response to the extract was diminished in a significant way (p < 0.
The first 30 seconds after extract administration were carefully examined and every five seconds the mean blood pressure decreased an average of 5, 9, 10, 5 mmHg for the phentolamine, propranolol, atropine and hexamethonium blocked groups respectively.
The first response was accompanied by a rise in systemic blood pressure, which was reduced by hexamethonium, not entirely eliminated by phentolamine but eliminated with spinal destruction to the sacral cord level.
China) Hexamethonium (BDH), Nifedipine (Alison's Drug Company), Tolazoline (Sigma) Propanol (Sigma).
Hexamethonium, a ganglion blocker, promethazine and chlorpheniramine, both of which are [H.
Hexamethonium bromide and acetylcholine chloride were purchased from Sigma Chemical Co.
Furthermore, the observed increases in both maximal percent and absolute decreases in MAP, in response to hexamethonium bromide after DOCA-salt treatment, further support the increased basal sympathetic activity in this model of hypertension.