CpG (a hexameric
motif) adjuvant can effectively improve the immunogenicity of DNA vaccine (Lipford et al., 1997; Davis et al., 1998; Li et al., 2016).
Adiponectin has different oligomeric isoforms, including trimeric, hexameric
, and the high molecular weight (HMW) oligomeric complex (18).
TNFalpha-induced NF-kappaB activation and cell oxidant production are modulated by hexameric
procyanidins in Caco-2 cells.
In serum, adiponectin is circulating in the form of 3 distinct oligomers, namely, a trimeric, a hexameric
, and a high-molecular-weight form (composedof 12-18 adiponectin molecules) (30).
Dimerization on formation of the high affinity hexameric
IL-6 receptor complex," The Journal of Biological Chemistry, vol.
GJs are made by docking of two hexameric
hemichannels (connexons) of two apposed cells, thus composed of 12 proteins called connexins.
MCM2 was a member of the MCM family (MCM2-7), and all 6 members of this family could form a hexameric
protein complex with each other.
Lodish, "T-cadherin is a receptor for hexameric
and high-molecular-weight forms of Acrp30/adiponectin," Proceedings of the National Academy of Sciences of the United States of America, vol.
Usually, adiponectin exists as a full-length protein of 30 kDa (fAd) that circulates in trimeric, hexameric
, and higher order complexes .
This trimer dimerizes to form a hexameric
complex composed of IL-6, IL-6R, and gp130  (Figure 6).
However, it was necessary for the insulin to take on a hexameric
form in order to have physical stability and an acceptable injection volume.
(23) Telomeres cap the ends of chromosomes and consist of hexameric
TTAGGG repeats and the protective 'shelterin' protein complex.