heterozygous


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het·er·o·zy·gous

(het'ĕr-ō-zī'gŭs),
Having different alleles at a given locus on the pair of chromosomes present in the diploid state; for example, having a normal beta globin gene (coding for normal hemoglobin, Hb A) at locus p15.5 on one chromosome 11 and an abnormal gene (coding for sickle-cell hemoglobin, Hb S) at the same locus on the other chromosome 11.

heterozygous

(hĕt′ər-ə-zī′gəs)
adj.
1. Having different alleles at one or more corresponding chromosomal loci.
2. Of or relating to a heterozygote.

het′er·o·zy·gos′i·ty (-ə-rō-zī-gŏs′ĭ-tē) n.

heterozygous

[het′ərəzī′gəs]
Etymology: Gk, heteros + zygotos, yoked
having two different alleles at corresponding loci on homologous chromosomes. An individual who is heterozygous for a trait has inherited an allele for that trait from one parent and an alternative allele from the other parent. An individual who is heterozygous for a genetic disease caused by a dominant allele, such as Huntington's disease, manifests the disorder. A person who is heterozygous for a hereditary disorder produced by a recessive allele, such as sickle cell anemia, is asymptomatic or exhibits reduced symptoms of the disease. The offspring of a heterozygous carrier of a genetic disorder have a 50% chance of inheriting the allele associated with the disorder if the other parent does not carry the allele. Compare homozygous.

het·er·o·zy·gous

(het'ĕr-ō-zī'gŭs)
Having different allelic genes at one locus or (by extension) many loci; heterotic.

heterozygous

Of a person carrying different genes at the same gene locus in corresponding chromosomes. The ALLELES are different. A single DOMINANT gene can manifest itself in a heterozygous person. Recessive genes are only manifest if both are present (HOMOZYGOUS).

Heterozygous

Two different genes controlling a specified inherited trait.

heterozygous

expression of inheritance of genetic disease, where the individual inherits the causative gene from only one parent, i.e. overt disease is not expressed or is expressed in mild form only in heterozygous indidivuals; see homozygous

het·er·o·zy·gous

(het'ĕr-ō-zī'gŭs)
Having different alleles at a given locus on the pair of chromosomes present in the diploid state.

heterozygous (het´ərōzī´gus),

adj a term indicating that genes lying at equivalent loci on chromosome pairs are different.

heterozygous

having different alleles at the one locus.
References in periodicals archive ?
About MC4 Heterozygous Deficiency Obesity MC4 heterozygous deficiency, also known as heterozygous MC4R mutation carriers, in which one of the genes for the MC4R are not fully functional, results in a strong predisposition to early onset and severe obesity and is the most common genetic cause of obesity.
Distribution of Mediterranean fever gene mutations in patients with ankylosing spondylitis Mediterranean fever mutations n % (n=29) * % (n=88) ** Heterozygous M694V mutation 10 34.
MD: major depression; AA: homozygous wild type; AG: heterozygous type; GG: homozygous mutant type; A: adenine; G: guanine Table 2.
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When run with control samples of each homozygous SNP genotype, HRM allows for the calling of homozygous or heterozygous sample SNP status by comparison of curve shapes.
To undertake molecular testing to identify the second FA-causing mutation in patients who were heterozygous for the founder mutation in the FANCG gene, as well as to determine whether or not other FANCG founder mutations exist in this population.
This study demonstrated significantly higher levels of acute-phase reactants in FMF patients homozygous and heterozygous for M694V mutations compared to those who did not have these mutations.
They pooled data from three randomized REVEAL trials on a total of 648 patients, identifying 399 (62%) participants who were negative for the epsilon-4 allele, 221 (34%) who were heterozygous carriers of the epsilon-4 allele, and 28 (4%) who were epsilon-4 homozygotes.
did not explore, namely regions where the father and mother of the fetus are both heterozygous.
Patient F was found to be heterozygous for the G85E (P.
Control somatic cells, GGTA1 knock-out heterozygous cells, and knock-in heterozygous cells expressing hDAF on GGTA1 locus (4x[10.