heterozygous


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het·er·o·zy·gous

(het'ĕr-ō-zī'gŭs),
Having different alleles at a given locus on the pair of chromosomes present in the diploid state; for example, having a normal beta globin gene (coding for normal hemoglobin, Hb A) at locus p15.5 on one chromosome 11 and an abnormal gene (coding for sickle-cell hemoglobin, Hb S) at the same locus on the other chromosome 11.

heterozygous

(hĕt′ər-ə-zī′gəs)
adj.
1. Having different alleles at one or more corresponding chromosomal loci.
2. Of or relating to a heterozygote.

het′er·o·zy·gos′i·ty (-ə-rō-zī-gŏs′ĭ-tē) n.

het·er·o·zy·gous

(het'ĕr-ō-zī'gŭs)
Having different allelic genes at one locus or (by extension) many loci; heterotic.

heterozygous

Of a person carrying different genes at the same gene locus in corresponding chromosomes. The ALLELES are different. A single DOMINANT gene can manifest itself in a heterozygous person. Recessive genes are only manifest if both are present (HOMOZYGOUS).

Heterozygous

Two different genes controlling a specified inherited trait.

het·er·o·zy·gous

(het'ĕr-ō-zī'gŭs)
Having different alleles at a given locus on the pair of chromosomes present in the diploid state.
References in periodicals archive ?
To undertake molecular testing to identify the second FA-causing mutation in patients who were heterozygous for the founder mutation in the FANCG gene, as well as to determine whether or not other FANCG founder mutations exist in this population.
He was found to exhibit compound heterozygous GNRHR mutations, Gln106Arg and Arg262Gln.
All patients of compound heterozygous for HbS and [beta]-thalassaemia (S[beta]) were anaemic (Hb = 3.5-10.22 g/dL).
In our study, a homozygous mutation c.1139_1141dupGC G(p.Gly380_Ala381insGly) and a heterozygous mutation c.1359_1361dupCGG(p.Gly456_Gln457insGly) were identified in FOXC1 in all subjects.
Yilmazet al., "Severe protein S deficiency associated with heterozygous factor V Leiden mutation in a child with purpura fulminans," Pediatric Hematology and Oncology, vol.
In patient 3, two novel heterozygous mutations were found in exon 18 of the NPHS1 gene.
* The report provides a snapshot of the global therapeutic landscape of Heterozygous familial hypercholesterolemia (heFH)
Hb-SD, a compound heterozygous disease, behaves like a Sickle cell disease with vaso-occlusive event occurring similarly and requires immediate recognition, management and possible counseling for future care.
Heterozygous patients should have more strong clinical evidence regarding FMF because they can actually have FMF or merely be carriers.
Food and Drug Administration (FDA) approved the first of these drugs, alirocumab (Praluent), for use by patients who have a hereditary form of high cholesterol, heterozygous familial hypercholesterolemia (HeFH), or patients who have had heart attacks or strokes due to cardiovascular disease.
Traditionally, ADO is defined as the random amplification failure of 1 of the 2 heterozygous alleles, whereas PA is defined as a bias that favors the amplification of one allele over the other, leading to failure to reach the threshold of detection (21).
Subjects without the IL-6 SNP-174G/C gene polymorphism (46.8%) and those with heterozygous polymorphism (42.6%) were represented in closely equal number, while trauma patients with homozygous polymorphism were represented in a statistically significantly lower number ([chi square]-test; p=0.004).