heterozygous


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het·er·o·zy·gous

(het'ĕr-ō-zī'gŭs),
Having different alleles at a given locus on the pair of chromosomes present in the diploid state; for example, having a normal beta globin gene (coding for normal hemoglobin, Hb A) at locus p15.5 on one chromosome 11 and an abnormal gene (coding for sickle-cell hemoglobin, Hb S) at the same locus on the other chromosome 11.
Farlex Partner Medical Dictionary © Farlex 2012

heterozygous

(hĕt′ər-ə-zī′gəs)
adj.
1. Having different alleles at one or more corresponding chromosomal loci.
2. Of or relating to a heterozygote.
het′er·o·zy·gos′i·ty (-ə-rō-zī-gŏs′ĭ-tē) n.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

het·er·o·zy·gous

(het'ĕr-ō-zī'gŭs)
Having different allelic genes at one locus or (by extension) many loci; heterotic.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

heterozygous

Of a person carrying different genes at the same gene locus in corresponding chromosomes. The ALLELES are different. A single DOMINANT gene can manifest itself in a heterozygous person. Recessive genes are only manifest if both are present (HOMOZYGOUS).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Heterozygous

Two different genes controlling a specified inherited trait.
Mentioned in: Hemoglobin Electrophoresis
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

het·er·o·zy·gous

(het'ĕr-ō-zī'gŭs)
Having different alleles at a given locus on the pair of chromosomes present in the diploid state.
Medical Dictionary for the Dental Professions © Farlex 2012
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References in periodicals archive ?
To undertake molecular testing to identify the second FA-causing mutation in patients who were heterozygous for the founder mutation in the FANCG gene, as well as to determine whether or not other FANCG founder mutations exist in this population.
Fanconi anaemia in black South African patients heterozygous for the FANCG c.637-643delTACCGCC founder mutation
He was found to exhibit compound heterozygous GNRHR mutations, Gln106Arg and Arg262Gln.
A Novel Mutation Ser34Phe in GNRHR causes Hypogonadotropic Hypogonadism during Pubertal Development in Boys
All patients of compound heterozygous for HbS and [beta]-thalassaemia (S[beta]) were anaemic (Hb = 3.5-10.22 g/dL).
A study of haemoglobinopathies and haemoglobin variants using high performance liquid chromatography (HPLC) in a teaching hospital of Odisha
In our study, a homozygous mutation c.1139_1141dupGC G(p.Gly380_Ala381insGly) and a heterozygous mutation c.1359_1361dupCGG(p.Gly456_Gln457insGly) were identified in FOXC1 in all subjects.
Novel Genetic Findings in a Chinese Family with Axenfeld-Rieger Syndrome
Yilmazet al., "Severe protein S deficiency associated with heterozygous factor V Leiden mutation in a child with purpura fulminans," Pediatric Hematology and Oncology, vol.
Protein C Deficiency Caused by a Novel Mutation in the PROC Gene in an Infant with Delayed Onset Purpura Fulminans
In patient 3, two novel heterozygous mutations were found in exon 18 of the NPHS1 gene.
Three Novel Mutations in the NPHS1 Gene in Vietnamese Patients with Congenital Nephrotic Syndrome
* The report provides a snapshot of the global therapeutic landscape of Heterozygous familial hypercholesterolemia (heFH)
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Hb-SD, a compound heterozygous disease, behaves like a Sickle cell disease with vaso-occlusive event occurring similarly and requires immediate recognition, management and possible counseling for future care.
Haemoglobin sickle D disease: A presentation with ischaemic stroke
Heterozygous patients should have more strong clinical evidence regarding FMF because they can actually have FMF or merely be carriers.
Bone mineral density in Egyptian children with familial Mediterranean fever
Food and Drug Administration (FDA) approved the first of these drugs, alirocumab (Praluent), for use by patients who have a hereditary form of high cholesterol, heterozygous familial hypercholesterolemia (HeFH), or patients who have had heart attacks or strokes due to cardiovascular disease.
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Traditionally, ADO is defined as the random amplification failure of 1 of the 2 heterozygous alleles, whereas PA is defined as a bias that favors the amplification of one allele over the other, leading to failure to reach the threshold of detection (21).
Embryo genome profiling by single-cell sequencing for preimplantation genetic diagnosis in a [beta]-thalassemia family
Subjects without the IL-6 SNP-174G/C gene polymorphism (46.8%) and those with heterozygous polymorphism (42.6%) were represented in closely equal number, while trauma patients with homozygous polymorphism were represented in a statistically significantly lower number ([chi square]-test; p=0.004).
Clinical relevance of IL-6 gene polymorphism in severely injured patients

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