Intra-population
heterozygosity and analysis of inbreeding coefficient: FIS and
heterozygosity of Chinese pond turtle were estimated for each population by12 microsatellite loci (table 6).
The average
heterozygosity of both Pakistani sheep breeds is lower than Chinese goat populations 0.677 to 0.737 (49) and 0.77 to 0.821 (50) and higher then some of the Indian goat and sheep breed values 0.426 and 0.501 (9, 51).
The Fixation Index (F), or Inbreeding coefficient, or
Heterozygosity deficit, showed that the cultured population possessed excess
heterozygosity with a negative coefficient of -0.173 [+ or -] 0.209, perhaps due to selection for heterozygotes through negative assortative mating.
Although there were no significant differences between values, the contrasting
heterozygosity (Ho) between the two populations evidenced higher
heterozygosity (Ho) in adults and sub-adults from the JNP, and lower
heterozygosity (Ho) in both categories from the urban parks, fact that reveals the inbreeding process in fragmented populations (Table 1).
High levels of expected
heterozygosity can be attributed to some factors such level of inbreeding, low selection pressure and high allele number.
Subsequently NPR2
heterozygosity has been identified in patients evaluated for ISS in studies by Wang et al.
Here, we present a first report of inadvertent transplantation of a liver from a donor with C282Y/H63D compound
heterozygosity into a nonhemochromatotic recipient.
Of these, the mutations p.Asn76Thr and p.Cys698Arg were detected in compound
heterozygosity with the most frequently detected mutation c.5714+5G>A (intron 40) in one male (ABCA4-47A, Supplementary Figures 1A and B) and one female patient (ABCA4-27A, Supplementary Figures 2A and B), respectively.
The five polymorphisms used included DdeI which is previously reported to be the most prevalent among neighboring Indian population.9 The current study reconfirms the
heterozygosity rate of DdeI in Pakistani HB population of Khyber Pakhtunkhwa (KP) province and Federally Administered Tribal Areas (FATA).
Allele frequencies,
heterozygosity values, and polymorphism information content (PIC) of each marker were determined by genotyping genomic DNA samples from 2 ethnic populations.
Alleles were scored using GeneMapper software (Applied Biosystems) and Saga[TM] software (LI-COR) then inputted into POPGENE (Yeh and Boyle, 1997) for analysis of observed and expected
heterozygosity and allelic variation.
The founder effect on genetic variability of experimental populations of mosquito fish were measured by the allozymes electrophoretic technique by Leberg (1992), who estimated the values of proportion of polymorphic loci, number of alleles per locus and
heterozygosity. Compared to source populations, Leberg found that 23 populations had a smaller He and 15 had an equal or greater He.
